Jump to content
 







Main menu
    


Navigation  


●Main page
 ●Contents
 ●Current events
 ●Random article
 ●About Wikipedia
 ●Contact us
 ●Donate
  



Contribute  


●Help
 ●Learn to edit
 ●Community portal
 ●Recent changes
 ●Upload file
  







Search  

































●Create account

●Log in
 









●Create account
 ● Log in
  



Pages for logged out editors learn more  


●Contributions
 ●Talk
  


















Contents

   



(Top)
  


1 Function  




2 References  




3 Further reading  













MYL9






●العربية
 ●مصرى
 ●日本語
 ●Українська
  
Edit links
  








●Article
 ●Talk
  
















●Read
 ●Edit
 ●View history
  







Tools
    


Actions  


●Read
 ●Edit
 ●View history
  



General  


●What links here
 ●Related changes
 ●Upload file
 ●Special pages
 ●Permanent link
 ●Page information
 ●Cite this page
 ●Get shortened URL
 ●Download QR code
 ●Wikidata item
  



Print/export  


●Download as PDF
 ●Printable version
  















Appearance
    

 





From Wikipedia, the free encyclopedia
  

MYL9
Identifiers
AliasesMYL9, LC20, MLC-2C, MLC2, MRLC1, MYRL2, myosin light chain 9, MMIHS4
External IDsOMIM: 609905; MGI: 2138915; HomoloGene: 21230; GeneCards: MYL9; OMA:MYL9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

10398

98932

Ensembl

ENSG00000101335

ENSMUSG00000067818

UniProt

P24844

Q9CQ19

RefSeq (mRNA)

NM_181526
NM_006097

NM_172118

RefSeq (protein)

NP_006088
NP_852667

NP_742116

Location (UCSC)Chr 20: 36.54 – 36.55 MbChr 2: 156.62 – 156.62 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Myosin regulatory light polypeptide 9 is a protein that in humans is encoded by the MYL9 gene.[5]

Function[edit]

Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000101335 – Ensembl, May 2017
  • ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000067818 – Ensembl, May 2017
  • ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ Kumar CC, Mohan SR, Zavodny PJ, Narula SK, Leibowitz PJ (May 1989). "Characterization and differential expression of human vascular smooth muscle myosin light chain 2 isoform in nonmuscle cells". Biochemistry. 28 (9): 4027–35. doi:10.1021/bi00435a059. PMID 2526655.
  • ^ "Entrez Gene: myosin".

    • Further reading[edit]

  • Szczesna-Cordary D, Guzman G, Zhao J, et al. (2005). "The E22K mutation of myosin RLC that causes familial hypertrophic cardiomyopathy increases calcium sensitivity of force and ATPase in transgenic mice". J. Cell Sci. 118 (Pt 16): 3675–83. doi:10.1242/jcs.02492. PMID 16076902. S2CID 19633613.
  • Deloukas P, Matthews LH, Ashurst J, et al. (2001). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Iwasaki T, Murata-Hori M, Ishitobi S, Hosoya H (2001). "Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells". Cell Struct. Funct. 26 (6): 677–83. doi:10.1247/csf.26.677. PMID 11942626.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Higashihara M, Watanabe M, Usuda S, Miyazaki K (2008). "Smooth muscle type isoform of 20 kDa myosin light chain is expressed in monocyte/macrophage cell lineage". Journal of Smooth Muscle Research = Nihon Heikatsukin Gakkai Kikanshi. 44 (1): 29–40. doi:10.1540/jsmr.44.29. PMID 18480596.
  • Kumar CC, Mohan SR, Zavodny PJ, et al. (1989). "Characterization and differential expression of human vascular smooth muscle myosin light chain 2 isoform in nonmuscle cells". Biochemistry. 28 (9): 4027–35. doi:10.1021/bi00435a059. PMID 2526655.

    • This article incorporates text from the United States National Library of Medicine, which is in the public domain.

    Stub icon

    This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by expanding it.

  • t
  • e

    • Retrieved from "https://en.wikipedia.org/w/index.php?title=MYL9&oldid=1191151764"
    Categories: 
    ●Genes on human chromosome 20
     ●EF-hand-containing proteins
     ●Human chromosome 20 gene stubs
     Hidden categories: 
    ●Articles with short description
     ●Short description matches Wikidata
     ●Wikipedia articles incorporating text from the United States National Library of Medicine
     ●All stub articles
      


    ●This page was last edited on 21 December 2023, at 20:54 (UTC).
    ●Text is available under the Creative Commons Attribution-ShareAlike License 4.0; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization.


    ●Privacy policy
    ●About Wikipedia
    ●Disclaimers
    ●Contact Wikipedia
    ●Code of Conduct
    ●Developers
    ●Statistics
    ●Cookie statement
    ●Mobile view


    Wikimedia Foundation
    Powered by MediaWiki