Retinoblastoma-binding protein 6 is a protein that in humans is encoded by the RBBP6 gene.[5][6][7]
The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.[7]
RBBP6 has been shown to interact with Y box binding protein 1.[8]
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