Identifiers
3-allyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
C19H21NO2
295.382 g·mol−1
3D model (JSmol)
c3ccccc3C2CN(CC=C)CCc(cc1O)c2cc1O
InChI=1S/C19H21NO2/c1-2-9-20-10-8-15-11-18(21)19(22)12-16(15)17(13-20)14-6-4-3-5-7-14/h2-7,11-12,17,21-22H,1,8-10,13H2
Key:QBUVZVXIRYFENV-UHFFFAOYSA-N
SKF-77,434 is a drug which acts as a selective dopamine D1 receptor partial agonist, and has stimulant and anorectic effects. Unlike other D1 agonists with higher efficacy such as SKF-81,297 and 6-Br-APB, SKF-77,434 does not maintain self-administration in animal studies, and so has been researched as a potential treatment for cocaine addiction.[1][2][3][4][5][6][7]
Others
PAMs
Antagonists
Antagonists