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(Top) 1 Reactions 2 Uses 3 Structure 4 See also 5 References 6 External links

Sodium propionate

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Sodium propionate^[1]
Names

Preferred IUPAC name Sodium propanoate
Other names Sodium propionate Napropion E281
Identifiers
CAS Number	137-40-6^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:132106^N
ChEMBL	ChEMBL500826^Y
ChemSpider	8399^Y
ECHA InfoCard	100.004.810
EC Number	205-290-4
E number	E281 (preservatives)
PubChem CID	8724
UNII	DK6Y9P42IN^Y
CompTox Dashboard (EPA)	DTXSID7021996
InChI InChI=1S/C3H6O2.Na/c1-2-3(4)5;/h2H2,1H3,(H,4,5);/q;+1/p-1^Y Key: JXKPEJDQGNYQSM-UHFFFAOYSA-M^Y InChI=1/C3H6O2.Na/c1-2-3(4)5;/h2H2,1H3,(H,4,5);/q;+1/p-1 Key: JXKPEJDQGNYQSM-REWHXWOFAH
SMILES [Na+].[O-]C(=O)CC
Properties
Chemical formula	C₃H₅NaO₂
Molar mass	96.060 g/mol
Appearance	Transparent crystals
Odor	faint acetic-butyric odor
Melting point	289 °C (552 °F; 562 K)
Solubility in water	1 g/ml
Solubilityinethanol	41.7 g/L
Pharmacology
ATC code	S01AX10 (WHO) QA16QA02 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references

Sodium propanoateorsodium propionate is the sodium saltofpropionic acid which has the chemical formula Na(C₂H₅C O O). This white crystalline solid is deliquescent in moist air.

Reactions[edit]

It is produced by the reaction of propionic acid and sodium carbonateorsodium hydroxide.

Uses[edit]

It is used as a food preservative and is represented by the food labeling E number E281 in Europe; it is used primarily as a mold inhibitor in bakery products. It is approved for use as a food additive in the EU,^[2] USA^[3] and Australia and New Zealand^[4] (where it is listed by its INS number 281).

Structure[edit]

Structure of sodium propionate, with methyl groups and H atoms omitted.^[5] Color code: red = O, blue = Na.

Anhydrous sodium propionate is a polymeric structure, featuring trigonal prismatic Na⁺ centers bonded to six oxygen ligands provided by the carboxylates. A layered structure is observed, with the hydrophobic ethyl groups projecting into the layered galleries. With hydrated sodium propionate, some of these Na-carboxylate linkages are displaced by water.

References[edit]

^ Merck Index, 11th Edition, 8623.

^ UK Food Standards Agency: "Current EU approved additives and their E Numbers". Retrieved 2011-10-27.

^ US Food and Drug Administration: "Listing of Food Additives Status Part II". Food and Drug Administration. Retrieved 2011-10-27.

^ Australia New Zealand Food Standards Code"Standard 1.2.4 - Labelling of ingredients". Retrieved 2011-10-27.

^ Fábry, Jan; Samolová, Erika (2020). "Layered alkali propanoatesM+(C2H5COO)−;M+= Na+, K+, Rb+, Cs+". Acta Crystallographica Section E. 76 (9): 1508–1513. Bibcode:2020AcCrE..76.1508F. doi:10.1107/S2056989020011469. PMC 7472758. PMID 32939309.

External links[edit]

Sodium propanoate at Sci-toys.com

v t e Ophthalmologicals: anti-infectives (S01A)
Antibiotics	amphenicols (Chloramphenicol Azidamfenicol) tetracyclines (Tetracycline Chlortetracycline Oxytetracycline) aminoglycosides (Dihydrostreptomycin Neomycin Framycetin Kanamycin Amikacin Tobramycin Gentamicin Netilmicin Micronomicin) macrolides (Erythromycin Natamycin) beta-lactams (Ampicillin Benzylpenicillin) polypeptides (Polymyxin B Tyrothricin) Rifamycin Fusidic acid
Sulfonamides	Sulfacetamide Sulfadicramide Sulfafenazol Sulfafurazole Sulfamethizole
Antivirals	Aciclovir Famciclovir Fomivirsen Ganciclovir Idoxuridine Interferon Trifluridine Vidarabine
Fluoroquinolones	Besifloxacin Ciprofloxacin Gatifloxacin Levofloxacin (+dexamethasone) Lomefloxacin Moxifloxacin Norfloxacin Ofloxacin Tosufloxacin
Other	Bibrocathol Chlorhexidine Dibrompropamidine Hexamidine Nitrofural Picloxydine Polihexanide Povidone-iodine Propamidine Resorcinol Sodium borate Sodium propionate

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