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Clinical data | |
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AHFS/Drugs.com | International Drug Names |
MedlinePlus | a601049 |
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Routes of administration | Oral |
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Pharmacokinetic data | |
Excretion | Excreted unchanged in urine |
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CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.004.418 |
Chemical and physical data | |
Formula | C11H13N3O3S |
Molar mass | 267.30 g·mol−1 |
3D model (JSmol) | |
Melting point | 194 °C (381 °F) |
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NY (what is this?) (verify) |
Sulfafurazole (INN, also known as sulfisoxazole) is a sulfonamide antibacterial with an dimethyl-isoxazole substituent. It possesses antibiotic activity against a wide range of Gram-negative and Gram-positive organisms.[1] It is sometimes given in combination with erythromycin (see erythromycin/Sulfafurazole) or phenazopyridine. It is used locally in a 4% solution or ointment.
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Antifolates (inhibit bacterial purine metabolism, thereby inhibiting DNA and RNA synthesis) |
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Quinolones (inhibit bacterial topoisomerase and/or DNA gyrase, thereby inhibiting DNA replication) |
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Anaerobic DNA inhibitors |
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RNA synthesis |
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