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(Top)
 


1 Medical uses  





2 References  














Tildipirosin






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Tildipirosin
Clinical data
Trade namesZuprevo
License data
Routes of
administration
Intramuscular, subcutaneous
ATCvet code
Legal status
Legal status
  • US: ℞-only[1][2]
  • EU: Rx-only[3]
  • Identifiers
        • (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4S,5S,6R)-4-(Dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-5,9,13-trimethyl-7-(2-piperidin-1-ylethyl)-15-(piperidin-1-ylmethyl)-1-oxacyclohexadeca-11,13-diene-2,10-dione
    • (4R,5S,6S,7R,9R,11E,13E,15R,16R)-16-Ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxo-7-[2-(1-piperidinyl)ethyl]-15-(1-piperidinylmethyl)oxacyclohexadeca-11,13-dien-6-yl 3,6-dideoxy-3-(dimethylamino)-β-D-glucopyranoside
    CAS Number
    PubChem CID
    DrugBank
    ChemSpider
    UNII
    ChEMBL
    CompTox Dashboard (EPA)
    ECHA InfoCard100.168.011 Edit this at Wikidata
    Chemical and physical data
    FormulaC41H71N3O8
    Molar mass734.032 g·mol−1
    3D model (JSmol)
    • CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O)N(C)C)O)CCN3CCCCC3)C)\C)CN4CCCCC4

    • InChI=1S/C41H71N3O8/c1-8-35-32(26-44-20-13-10-14-21-44)23-27(2)15-16-33(45)28(3)24-31(17-22-43-18-11-9-12-19-43)40(29(4)34(46)25-36(47)51-35)52-41-39(49)37(42(6)7)38(48)30(5)50-41/h15-16,23,28-32,34-35,37-41,46,48-49H,8-14,17-22,24-26H2,1-7H3/b16-15+,27-23+/t28-,29+,30-,31+,32-,34-,35-,37+,38-,39-,40-,41+/m1/s1

    • Key:HNDXPZPJZGTJLJ-UEJFNEDBSA-N

    Tildipirosin, sold under the brand name Zuprevo is an antibiotic used in pigs and cattle.[1][3]

    Medical uses[edit]

    In the United States, tildipirosin is indicated for the treatment or control of bovine respiratory disease associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni in beef and non-lactating dairy cattle.[1]

    In the European Union, tildipirosin is indicated for the treatment and metaphylaxis of swine respiratory disease associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica, and Haemophilus parasuis sensitive to tildipirosin;[3] and for the treatment and prevention of bovine respiratory disease associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni sensitive to tildipirosin.[3]

    References[edit]

    1. ^ a b c "Zuprevo- tildipirosin injection, solution". DailyMed. U.S. National Library of Medicine. 11 January 2013. Retrieved 21 August 2023.
  • ^ Budde JA, McCluskey DM (2023). Plumb's Veterinary Drug Handbook (Tenth ed.). Wiley. p. 1235. ISBN 978-1-394-17220-7.
  • ^ a b c d "Zuprevo EPAR". European Medicines Agency. 3 February 2022. Retrieved 21 August 2023. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.

  • t
  • e

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=Tildipirosin&oldid=1183932920"

    Categories: 
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    This page was last edited on 7 November 2023, at 10:31 (UTC).

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