Main menu Navigation ●Main page ●Contents ●Current events ●Random article ●About Wikipedia ●Contact us ●Donate Contribute ●Help ●Learn to edit ●Community portal ●Recent changes ●Upload file

●Create account ●Log in ●Create account ● Log in Pages for logged out editors learn more ●Contributions ●Talk

(Top) 1 References 2 External links

Rokitamycin

●فارسی ●Italiano ●日本語 ●Српски / srpski ●Srpskohrvatski / српскохрватски ●ไทย ●中文 Edit links ●Article ●Talk ●Read ●Edit ●View history Tools Actions ●Read ●Edit ●View history General ●What links here ●Related changes ●Upload file ●Special pages ●Permanent link ●Page information ●Cite this page ●Get shortened URL ●Download QR code ●Wikidata item Print/export ●Download as PDF ●Printable version Appearance From Wikipedia, the free encyclopedia

Rokitamycin
Clinical data

AHFS/Drugs.com	International Drug Names
ATC code	J01FA12 (WHO)
Identifiers
IUPAC name (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-2,4-dimethyl-4-propoxyoxan-3-yl butanoate
CAS Number	74014-51-0^N
PubChem CID	5282211
ChemSpider	4445397^Y
UNII	ZPT03UEM0E
ChEMBL	ChEMBL1908350^N
CompTox Dashboard (EPA)	DTXSID6023521
Chemical and physical data
Formula	C₄₂H₇₁NO₁₄
Molar mass	814.023 g·mol⁻¹
3D model (JSmol)	Interactive image
Melting point	116 °C (241 °F)
Solubility in water	Insoluble in water; Very soluble in chloroform and methanol; Almost completely (>99.5%) in ethanol and acetonitrile. mg/mL (20 °C)
SMILES O=CC[C@H]3C[C@@H](C)[C@@H](O)/C=C/C=C/C[C@H](OC(=O)C[C@@H](O)[C@H](OC)[C@H]3O[C@@H]2O[C@@H]([C@@H](O[C@@H]1O[C@H]([C@H](OC(=O)CCC)[C@](OC(=O)CC)(C1)C)C)[C@H](N(C)C)[C@H]2O)C)C
InChI InChI=1S/C42H69NO15/c1-11-16-32(48)55-40-27(6)53-34(23-42(40,7)58-31(47)12-2)56-37-26(5)54-41(36(50)35(37)43(8)9)57-38-28(19-20-44)21-24(3)29(45)18-15-13-14-17-25(4)52-33(49)22-30(46)39(38)51-10/h13-15,18,20,24-30,34-41,45-46,50H,11-12,16-17,19,21-23H2,1-10H3/b14-13+,18-15+/t24-,25-,26-,27+,28+,29+,30-,34+,35-,36-,37-,38+,39+,40+,41+,42-/m1/s1^Y Key:VYWWNRMSAPEJLS-MDWYKHENSA-N^Y
^NY (what is this?) (verify)

Rokitamycin is a macrolide antibiotic synthesized from strains of Streptomyces kitasatoensis.^[1]

References[edit]

^ Braga PC (April 2002). "Rokitamycin: bacterial resistance to a 16-membered ring macrolide differs from that to 14- and 15-membered ring macrolides". Journal of Chemotherapy. 14 (2). Florence, Italy: 115–31. doi:10.1179/joc.2002.14.2.115. PMID 12017366. S2CID 1250525.

-mycin (Streptomyces)

-micin (Micromonospora)

other

Tetracyclines

Macrolides	Azithromycin^# Boromycin Carbomycin Carrimycin Clarithromycin^# Dirithromycin Erythromycin^# Flurithromycin Gamithromycin Josamycin Kitasamycin Midecamycin Miocamycin Oleandomycin Rokitamycin Roxithromycin Solithromycin Spiramycin Telithromycin Tildipirosin Tilmicosin Troleandomycin Tulathromycin Tylosin Tylvalosin
Ketolides	Telithromycin^‡ Cethromycin Solithromycin^†
Lincosamides	Clindamycin^# Lincomycin Pirlimycin
Streptogramins	Pristinamycin (IA, IIA, IIB) NXL103 (Flopristin, Linopristin) Quinupristin/dalfopristin (Dalfopristin, Quinupristin) Streptogramin A Streptogramin B Virginiamycin (S1)

Steroid antibacterials

^‡Withdrawn from market

This systemic antibiotic-related article is a stub. You can help Wikipedia by expanding it.