Jump to content
 







Main menu
    


Navigation  


●Main page
 ●Contents
 ●Current events
 ●Random article
 ●About Wikipedia
 ●Contact us
 ●Donate
  



Contribute  


●Help
 ●Learn to edit
 ●Community portal
 ●Recent changes
 ●Upload file
  







Search  

































●Create account

●Log in
 









●Create account
 ● Log in
  



Pages for logged out editors learn more  


●Contributions
 ●Talk
  


















Contents

   



(Top)
  


1 Pharmacokinetics  




2 Legal Status  




3 See also  




4 References  




5 External links  













Ethylone






●Български
 ●Français
 ●Polski
 ●Српски / srpski
 ●Srpskohrvatski / српскохрватски
 ●Suomi
  
Edit links
  








●Article
 ●Talk
  
















●Read
 ●Edit
 ●View history
  







Tools
    


Actions  


●Read
 ●Edit
 ●View history
  



General  


●What links here
 ●Related changes
 ●Upload file
 ●Special pages
 ●Permanent link
 ●Page information
 ●Cite this page
 ●Get shortened URL
 ●Download QR code
 ●Wikidata item
  



Print/export  


●Download as PDF
 ●Printable version
  















Appearance
    

 





From Wikipedia, the free encyclopedia
  

Ethylone
Clinical data
Pregnancy
category
  • N (US)
Routes of
administration		Oral, nasal, IV
Legal status
Legal status
  • DE: Anlage I (Authorized scientific use only)
  • UK: Class B
  • UN: Psychotropic Schedule II[2]
    • Identifiers

    • (RS)-1-(1,3-benzodioxol-5-yl)-2-(ethylamino)propan-1-one

    CAS Number
    PubChem CID
    ChemSpider
    UNII
    KEGG
    CompTox Dashboard (EPA)
    Chemical and physical data
    FormulaC12H15NO3
    Molar mass221.256 g·mol−1
    3D model (JSmol)
    ChiralityRacemic mixture

    • CC(NCC)C(=O)c1ccc2OCOc2c1

    • InChI=1S/C12H15NO3/c1-3-13-8(2)12(14)9-4-5-10-11(6-9)16-7-15-10/h4-6,8,13H,3,7H2,1-2H3 ☒N

    • Key:MJEMIOXXNCZZFK-UHFFFAOYSA-N ☒N

     ☒NcheckY (what is this?)  (verify)

    Ethylone, also known as 3,4-methylenedioxy-N-ethylcathinone (MDEC, βk-MDEA), is a recreational designer drug classified as an entactogen, stimulant, and psychedelic of the phenethylamine, amphetamine, and cathinone chemical classes. It is the β-keto analogueofMDEA ("Eve"). Ethylone has only a short history of human use and is reported to be less potent than its relative methylone.[citation needed] In the United States, it began to be found in cathinone products in late 2011.[3]

    Very little data exists about the pharmacological properties, metabolism, and toxicity of ethylone, and although several ethylone-related deaths have been reported, the cause of death was not due to ingestion of ethylone.[3]

    Pharmacokinetics[edit]

    Analysis of human and rat urine for the metabolites of bk-amphetamines suggested that ethylone was degraded in the following metabolic steps:[4]

    1. N-deethylation to the primary amine.
    2. Reduction of the keto moiety to the respective alcohol.

    Legal Status[edit]

    As of October 2015 Ethylone is a controlled substance in China.[5]

    See also[edit]

    References[edit]

    1. ^ Anvisa (2023-07-24). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-07-25). Archived from the original on 2023-08-27. Retrieved 2023-08-27.
  • ^ "Substance Details Ethylone". Retrieved 2024-01-22.
  • ^ a b Lee D, Chronister CW, Hoyer J, Goldberger BA (September 2015). "Ethylone-Related Deaths: Toxicological Findings". Journal of Analytical Toxicology. 39 (7): 567–71. doi:10.1093/jat/bkv053. PMID 26025164.
  • ^ Meyer MR, Wilhelm J, Peters FT, Maurer HH (June 2010). "Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography-mass spectrometry". Analytical and Bioanalytical Chemistry. 397 (3): 1225–33. doi:10.1007/s00216-010-3636-5. PMID 20333362. S2CID 21471611.
  • ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.

    • External links[edit]

    Stub icon

    This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.

  • t
  • e

    • Retrieved from "https://en.wikipedia.org/w/index.php?title=Ethylone&oldid=1228529150"
    Categories: 
    ●Cathinones
     ●Psychedelic phenethylamines
     ●Entactogens and empathogens
     ●Benzodioxoles
     ●Designer drugs
     ●Serotonin-norepinephrine-dopamine releasing agents
     ●Substituted amphetamines
     ●Nervous system drug stubs
     Hidden categories: 
    ●CS1 Brazilian Portuguese-language sources (pt-br)
     ●CS1 Chinese-language sources (zh)
     ●Articles with short description
     ●Short description matches Wikidata
     ●Articles with changed CASNo identifier
     ●Articles with changed ChemSpider identifier
     ●Articles with changed KEGG identifier
     ●Articles with changed InChI identifier
     ●Articles without EBI source
     ●Chemical pages without DrugBank identifier
     ●Drugs missing an ATC code
     ●Drugboxes which contain changes to verified fields
     ●Drugboxes which contain changes to watched fields
     ●All articles with unsourced statements
     ●Articles with unsourced statements from May 2015
     ●All stub articles
      


    ●This page was last edited on 11 June 2024, at 18:53 (UTC).
    ●Text is available under the Creative Commons Attribution-ShareAlike License 4.0; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization.


    ●Privacy policy
    ●About Wikipedia
    ●Disclaimers
    ●Contact Wikipedia
    ●Code of Conduct
    ●Developers
    ●Statistics
    ●Cookie statement
    ●Mobile view


    Wikimedia Foundation
    Powered by MediaWiki