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Contents

   



(Top)
 


1 History  





2 Modified mechanisms  





3 Legal status  





4 See also  





5 References  














MON 863: Difference between revisions






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==History==

==History==



In 2004 Monsanto sought approval in Europe to introduce MON 863, which led to controversy over acceptance by regulatory bodies of industry-funded toxicity studies and over the design of those studies. Pr Gilles Eric Séralini, who was on the committee that reviewed MON863 for the French government,<ref>[http://www.criigen.org/SiteEn/index.php?option=com_content&task=view&id=57&Itemid=105 Seralini bio on CRIIGEN]</ref> was a major figure in those controversies and continues to be a critic of toxicity study design.<ref>{{cite journal |doi=10.1016/j.fct.2012.08.005 |title=Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize |year=2012 |last1=Séralini |first1=Gilles-Eric |last2=Clair |first2=Emilie |last3=Mesnage |first3=Robin |last4=Gress |first4=Steeve |last5=Defarge |first5=Nicolas |last6=Malatesta |first6=Manuela |last7=Hennequin |first7=Didier |last8=De Vendômois |first8=Joël Spiroux |journal=Food and Chemical Toxicology |volume=50 |issue=11 |pages=4221}}</ref><ref>{{cite doi |10.2903/j.efsa.2012.2910}}</ref>

In 2004 Monsanto sought approval in Europe to introduce MON 863, which led to controversy over acceptance by regulatory bodies of industry-funded toxicity studies and over the design of those studies. Pr Gilles Eric Séralini, who was on the committee that reviewed MON863 for the French government,<ref>[http://www.criigen.org/SiteEn/index.php?option=com_content&task=view&id=57&Itemid=105 Seralini bio on CRIIGEN]</ref> was a major figure in those controversies and continues to be a critic of toxicity study design.<ref>{{cite journal |doi=10.1016/j.fct.2012.08.005 |title=Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize |year=2012 |last1=Séralini |first1=Gilles-Eric |last2=Clair |first2=Emilie |last3=Mesnage |first3=Robin |last4=Gress |first4=Steeve |last5=Defarge |first5=Nicolas |last6=Malatesta |first6=Manuela |last7=Hennequin |first7=Didier |last8=De Vendômois |first8=Joël Spiroux |journal=Food and Chemical Toxicology |volume=50 |issue=11 |pages=4221}}</ref><ref>EFSA, 4 October 2012. [http://www.efsa.europa.eu/en/press/news/121004.htm Press release with summary of findings]. Full review: EFSA (2012) [http://www.efsa.europa.eu/en/efsajournal/doc/2910.pdf Review of the Séralini ''et al''. (2012) publication on a 2-year rodent feeding study with glyphosate formulations and GM maize NK603 as published online on 19 September 2012 in Food and Chemical Toxicology] EFSA Journal 2012;10(10):2910 doi=10.2903/j.efsa.2012.2910</ref>






Revision as of 15:06, 22 October 2012

MON 863 is a genetically engineered variety of maize produced by Monsanto.

History

In 2004 Monsanto sought approval in Europe to introduce MON 863, which led to controversy over acceptance by regulatory bodies of industry-funded toxicity studies and over the design of those studies. Pr Gilles Eric Séralini, who was on the committee that reviewed MON863 for the French government,[1] was a major figure in those controversies and continues to be a critic of toxicity study design.[2][3]


See Genetically modified food controversies for details of this controversy, which extended beyond MON 863 to all GMOs.

Following legal action by parties including the Swedish Board of Agriculture and Greenpeace, a Münster appeals court ruled that Monsanto would be forced to publicly reveal its research data.[4]

Modified mechanisms

MON 863 is genetically altered to express a modified version of Cry3Bb1, a delta endotoxin which originates from Bacillus thuringiensis.[5][6] This protects the plant from corn rootworm.[6][7] Unlike MON 810, Bt 11, and Bt 176 which each produce a modified Cry1Ab, MON 863 instead produces a modified Cry3Bb1 toxin and contains nptII, a marker gene for antibiotic resistance.[5][8]

Legal status

MON 863 is approved for use in Australia, Canada, China, the European Union, Japan, Mexico, New Zealand, the Philippines, Russia, Singapore, South Korea, Taiwan, and the United States.[9][10]

See also

References

  • ^ Séralini, Gilles-Eric; Clair, Emilie; Mesnage, Robin; Gress, Steeve; Defarge, Nicolas; Malatesta, Manuela; Hennequin, Didier; De Vendômois, Joël Spiroux (2012). "Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize". Food and Chemical Toxicology. 50 (11): 4221. doi:10.1016/j.fct.2012.08.005.
  • ^ EFSA, 4 October 2012. Press release with summary of findings. Full review: EFSA (2012) Review of the Séralini et al. (2012) publication on a 2-year rodent feeding study with glyphosate formulations and GM maize NK603 as published online on 19 September 2012 in Food and Chemical Toxicology EFSA Journal 2012;10(10):2910 doi=10.2903/j.efsa.2012.2910
  • ^ Reilly, Michael (2010-01-23). "Is Genetically Modified Corn Toxic?". Discovery News. Retrieved 2010-07-21.
  • ^ a b "The MON863 case - a chronicle of systematic deception" (PDF). Greenpeace. Retrieved 2010-07-22. MON863 is a genetically modified corn that expresses a Bt-toxin. This toxin is a modified version of the delta endotoxin Cry3Bb1 which originates from the microorganism Bacillus thuringiensis. The genetic manipulation is aimed at protecting maize plants against a pest called corn rootworm (Diabrotica spp.). MON863 differs from other Bt-corns already placed on the market (MON810, BT11, Bt176), which produce a modified Cry1Ab toxin conferring resistance to a pest called European corn borer (Ostrinia nubilalis), in that it produces an artificial Cry3Bb1 toxin. In addition to the modified Cry3Bb1 toxin gene MON863 contains an antibiotic resistance marker gene.
  • ^ a b Doull, J.; Gaylor, D.; Greim, H.A.; Lovell, D.P.; Lynch, B.; Munro, I.C. (2007). "Report of an Expert Panel on the reanalysis by of a 90-day study conducted by Monsanto in support of the safety of a genetically modified corn variety (MON 863)". Food and Chemical Toxicology. 45 (11): 2073–85. doi:10.1016/j.fct.2007.08.033. PMID 17900781.
  • ^ Coghlan, Andy (2010-01-22). "Engineered maize toxicity claims roundly rebuffed". New Scientist. Retrieved 2010-07-21.
  • ^ Lorch, Antje (2005-09-30). "EFSA's Opinion on MON863 hybrids" (PDF). ifrik. Greenpeace. Retrieved 2010-07-22. MON863 contains an GM antibiotic resistance gene (nptII) against kanamycin and neomycin.
  • ^ "Technical & Safety Information - Focus on MON 863 / YieldGard Rootworm". Monsanto. Retrieved 2010-07-22. Based on these reviews, this maize has been authorized for planting in the United States and Canada since 2003 and is additionally approved for import and food use in many countries around the world, including Japan, Korea, Taiwan, the Philippines, Australia/New Zealand, China, Russia, Singapore, Mexico and the European Union. [dead link]
  • ^ Staff Focus on MON 863 / YieldGard® Rootworm Monsanto Consume, Technical And Safety Information, Accessed 5 April 2012

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=MON_863&oldid=519213749"

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    This page was last edited on 22 October 2012, at 15:06 (UTC).

    This version of the page has been revised. Besides normal editing, the reason for revision may have been that this version contains factual inaccuracies, vandalism, or material not compatible with the Creative Commons Attribution-ShareAlike License.



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