Jump to content

Main menu Navigation ●Main page ●Contents ●Current events ●Random article ●About Wikipedia ●Contact us ●Donate Contribute ●Help ●Learn to edit ●Community portal ●Recent changes ●Upload file

●Create account ●Log in ●Create account ● Log in Pages for logged out editors learn more ●Contributions ●Talk

(Top) 1 References

1,3-Difluoro-2-propanol

●تۆرکجه ●Català ●Čeština ●فارسی ●Српски / srpski ●Srpskohrvatski / српскохрватски ●தமிழ் ●中文 Edit links ●Article ●Talk ●Read ●Edit ●View history Tools Actions ●Read ●Edit ●View history General ●What links here ●Related changes ●Upload file ●Special pages ●Permanent link ●Page information ●Cite this page ●Get shortened URL ●Download QR code ●Wikidata item Print/export ●Download as PDF ●Printable version In other projects ●Wikimedia Commons Appearance From Wikipedia, the free encyclopedia

Names

Preferred IUPAC name

1,3-Difluoropropan-2-ol

Identifiers

CAS Number

453-13-4^N

3D model (JSmol)

Interactive image

Interactive image

ChemSpider

61300^Y

ECHA InfoCard

100.006.561

PubChem CID

67985

UNII

R8ZM2LQG7K^Y

CompTox Dashboard (EPA)

DTXSID1060009

InChI

InChI=1S/C3H6F2O/c4-1-3(6)2-5/h3,6H,1-2H2^Y

Key: PVDLUGWWIOGCNH-UHFFFAOYSA-N^Y
InChI=1/C3H6F2O/c4-1-3(6)2-5/h3,6H,1-2H2

Key: PVDLUGWWIOGCNH-UHFFFAOYAJ

SMILES

OC(CF)CF
FCC(O)CF

Properties

Chemical formula

C₃H₆F₂O

Molar mass

96.077 g·mol⁻¹

Density

1.24 g/cm³ (at 25 °C) ^[1]

Boiling point

54 to 55 °C (129 to 131 °F; 327 to 328 K)

Hazards

Flash point

42 °C (108 °F; 315 K)

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

N verify (what is ^YN ?)

Infobox references

1,3-Difluoro-2-propanol is a metabolic poison which disrupts the citric acid cycle and is used as a rodenticide, similar to sodium fluoroacetate. It is the main ingredient (along with 1-chloro-3-fluoro-2-propanol) in the rodenticide product Gliftor which was widely used in the former USSR^[2]^[3]^[4] and still approved in China.^[5]

References

[edit]

^ Sigma Aldrich

^ Buklan AI, Kravets AF (1986). "[Gliftor poisoning]". Sudebno-Meditsinskaia Ekspertiza (in Russian). 29 (1): 55–6. PMID 3961873.

^ Feldwick MG, Noakes PS, Prause U, Mead RJ, Kostyniak PJ (1998). "The biochemical toxicology of 1,3-difluoro-2-propanol, the major ingredient of the pesticide gliftor: the potential of 4-methylpyrazole as an antidote". Journal of Biochemical and Molecular Toxicology. 12 (1): 41–52. doi:10.1002/(SICI)1099-0461(1998)12:1<41::AID-JBT6>3.0.CO;2-P. PMID 9414486. S2CID 29455648.

^ Menon KI, Feldwick MG, Noakes PS, Mead RJ (2001). "The mode of toxic action of the pesticide gliftor: the metabolism of 1,3-difluoroacetone to (−)-erythro-fluorocitrate". Journal of Biochemical and Molecular Toxicology. 15 (1): 47–54. doi:10.1002/1099-0461(2001)15:1<47::AID-JBT6>3.0.CO;2-E. PMID 11170315. S2CID 9064673.

^ Wood, Alan. "Gliftor". Compendium of Pesticide Common Names. Retrieved 14 June 2021.