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1 See also  




2 References  













T-1152







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From Wikipedia, the free encyclopedia
  

T-1152
Names
Other names
  • TL-1178
  • Stedman's meta compound
    • Identifiers

    CAS Number

    3D model (JSmol)
    ChemSpider

    PubChem CID

    CompTox Dashboard (EPA)

    • InChI=1S/C11H16N2O2.HI/c1-12-11(14)15-10-7-5-6-9(8-10)13(2,3)4;/h5-8H,1-4H3;1H

      Key: MIAARRZWMRMHIS-UHFFFAOYSA-N

    • CNC(=O)OC1=CC=CC(=C1)[N+](C)(C)C.[I-]

    Hazards
    Lethal dose or concentration (LD, LC):

    LD50 (median dose)

    		 270 μg/kg (subcutaneous, mice)[1]
    115 μg/kg (intravenous, mice)[1]
    260 μg/kg (subcutaneous, rabbits)[1]

    LDLo (lowest published)

    		 2.5 mg/kg (oral, mice)[2]

    Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

    Infobox references

    T-1152 is a quaternary carbamate anticholinesterase. It is synthesized by reaction of m-dimethylaminophenol with methyl isocyanate, followed by quaternization with methyl iodide.[3] Since T-1152 is toxic by ingestion, it was patented as a rodenticide in 1932.[2]

    The chloride and methylsulfate salt of T-1152 is T-1690 (TL-1226) and AR-13, respectively.[1]

    See also[edit]

    References[edit]

    1. ^ a b c d Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
  • ^ a b "Product for destroying animals".
  • ^ Stedman, Edgar (1 January 1926). "Studies on the Relationship between Chemical Constitution and Physiological Action". Biochemical Journal. 20 (4): 719–734. doi:10.1042/bj0200719. PMC 1251776. PMID 16743713.

    • Retrieved from "https://en.wikipedia.org/w/index.php?title=T-1152&oldid=1223122884"
    Categories: 
    ●Carbamate nerve agents
     ●Acetylcholinesterase inhibitors
     ●Aromatic carbamates
     ●Phenol esters
     ●Quaternary ammonium compounds
     ●Iodides
     ●Rodenticides
     Hidden categories: 
    ●Articles without InChI source
     ●Articles without EBI source
     ●Articles without KEGG source
     ●Articles without UNII source
     ●Articles containing unverified chemical infoboxes
     ●Articles with short description
     ●Short description matches Wikidata
      


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