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(Top)
 


1 See also  





2 References  














Pindone






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From Wikipedia, the free encyclopedia
 


Pindone
Names
Preferred IUPAC name

2-(2,2-Dimethylpropanoyl)-1H-indene-1,3(2H)-dione

Other names

2-Pivaloyl-1,3-indandione

Identifiers

CAS Number

3D model (JSmol)

ChemSpider
ECHA InfoCard 100.001.330 Edit this at Wikidata
KEGG

PubChem CID

UNII

CompTox Dashboard (EPA)

  • InChI=1S/C14H14O3/c1-14(2,3)13(17)10-11(15)8-6-4-5-7-9(8)12(10)16/h4-7,10H,1-3H3 checkY

    Key: RZKYEQDPDZUERB-UHFFFAOYSA-N checkY

  • InChI=1/C14H14O3/c1-14(2,3)13(17)10-11(15)8-6-4-5-7-9(8)12(10)16/h4-7,10H,1-3H3

    Key: RZKYEQDPDZUERB-UHFFFAOYAX

  • O=C2c1ccccc1C(=O)C2C(=O)C(C)(C)C

Properties

Chemical formula

C14H14O3
Molar mass 230.26 g/mol
Appearance Bright-yellow powder[1]
Odor almost none
Density 1.06 g/mL
Melting point 110 °C (230 °F; 383 K)

Solubility in water

0.002% (25°C)[1]
Hazards
Lethal dose or concentration (LD, LC):

LD50 (median dose)

280 mg/kg (rat, oral)
75 mg/kg (dog, oral)
150 mg/kg (rabbit, oral)[2]
NIOSH (US health exposure limits):

PEL (Permissible)

TWA 0.1 mg/m3[1]

REL (Recommended)

TWA 0.1 mg/m3[1]

IDLH (Immediate danger)

100 mg/m3[1]

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

☒N verify (what is checkY☒N ?)

Infobox references

Pindone is an anticoagulant drug[3] for agricultural use. It is commonly used as a rodenticide in the management of rat and rabbit populations.

It is pharmacologically analogous to warfarin and inhibits the synthesis of Vitamin K-dependent clotting factors.

See also[edit]

References[edit]

  1. ^ a b c d e NIOSH Pocket Guide to Chemical Hazards. "#0516". National Institute for Occupational Safety and Health (NIOSH).
  • ^ "Pindone". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
  • ^ Robinson MH, Twigg LE, Wheeler SH, Martin GR (March 2005). "Effect of the anticoagulant, pindone, on the breeding performance and survival of merino sheep, Ovis aries". Comp. Biochem. Physiol. B. 140 (3): 465–73. doi:10.1016/j.cbpc.2004.11.011. PMID 15694595.

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  • Retrieved from "https://en.wikipedia.org/w/index.php?title=Pindone&oldid=1057048391"

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