The second roundofCONCACAF matches for 2022 FIFA World Cup qualification was played on 12 and 15 June 2021.[1]
A total of six teams advanced from the first round and played home-and-away over two legs in three ties. The three winners advanced to the third round.[2]
The first and second legs were originally scheduled for March 2021, but were later rescheduled to June 2021 due to the COVID-19 pandemic.[3]
Note: Bolded teams qualified for the third round.
| Group (first round) |
Winners |
|---|---|
| A |  El Salvador
|
| B |  Canada
|
| C |  Curaçao
|
| D |  Panama
|
| E |  Haiti
|
| F |  Saint Kitts and Nevis
|
The second round ties were predetermined as follows:
The winners of Groups D–F hosted the first leg, while the winners of Groups A–C hosted the second leg.
The matches were played on 12 and 15 June 2021.
| Team 1 | Agg.Tooltip Aggregate score | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Saint Kitts and Nevis
|
0–6 | El Salvador
|
0–4 | 0–2 |
| Haiti
|
0–4 | Canada
|
0–1 | 0–3 |
| Panama
|
2–1 | Curaçao
|
2–1 | 0–0 |
| Saint Kitts and Nevis | 0–4 | El Salvador |
|---|---|---|
| Report |
 20' 64' (pen.) |
Attendance: 0
Referee: Kevin Morrison (Jamaica)
| El Salvador | 2–0 | Saint Kitts and Nevis |
|---|---|---|
87' |
Report |
Attendance: 0
Referee: Keylor Herrera (Costa Rica)
El Salvador won 6–0 on aggregate and advanced to the third round.
| Haiti | 0–1 | Canada |
|---|---|---|
| Report |
|
Attendance: 0
Referee: John Pitti (Panama)
| Canada | 3–0 | Haiti |
|---|---|---|
|
74' 89' |
Report |
Attendance: 0
Referee: Rubiel Vazquez (United States)
Canada won 4–0 on aggregate and advanced to the third round.
| Panama | 2–1 | Curaçao |
|---|---|---|
77' |
Report |
|
Attendance: 7,000
Referee: Jaime Herrera Bonilla (El Salvador)
| Curaçao | 0–0 | Panama |
|---|---|---|
| Report |
Attendance: 2,760
Referee: Marco Ortíz (Mexico)
Panama won 2–1 on aggregate and advanced to the third round.
There were 13 goals scored in 6 matches, for an average of 2.17 goals per match.
2 goals
Joshua Pérez David Rugamas1 goal
Rangelo Janga Darwin Cerén Gerson Mayen Alberto Quintero Cecilio Waterman1 own goal
Josué Duverger (against Canada)
