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Adapalene | Retinoid |
Benzoyl peroxide | Peroxide |
Clinical data | |
Trade names | Epiduo, Epiduo Forte |
Routes of administration | Topical |
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Adapalene/benzoyl peroxide, sold under the brand name Epiduo among others, is a fixed-dose combination medication for the treatment of severe acne vulgaris.[1][2] It consists of a combination of adapalene and benzoyl peroxide in a topical gel formulation.[1][2]
It is available as a generic medication.[3]
Adapalene/benzoyl peroxide is indicated for the topical treatment of acne vulgaris.[1][2]
Commonly reported side effects include the following:[1][2]
Meta-analysis of clinical trials has shown this combined therapy to be more effective than either of its ingredients by themselves.[4]
The use of adapalene/benzoyl peroxide in combination with oral antibiotics (lymecycline) has been studied;[5] the combination was well tolerated and showed an improved success rate compared to those receiving only antibiotics (47.6% vs. 33.7%, P = 0.002).
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Antibacterial |
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Keratolytic |
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Anti-inflammatory |
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Antibiotics |
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Hormonal |
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Retinoids |
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Combinations |
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