| chemokine (C-C motif) ligand 15 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CCL15 | ||||||
| Alt. symbols | SCYA15, HCC-2, NCC-3, SCYL3, MIP-5, Lkn-1, MIP-1d, HMRP-2B | ||||||
| NCBI gene | 6359 | ||||||
| HGNC | 10613 | ||||||
| OMIM | 601393 | ||||||
| PDB | 2HCC | ||||||
| RefSeq | NM_032965 | ||||||
| UniProt | Q16663 | ||||||
| Other data | |||||||
| Locus | Chr. 17 q11.2 | ||||||
| |||||||
Chemokine (C-C motif) ligand 15 (CCL15) is a small cytokine belonging to the CC chemokine family that is also known as leukotactin-1, MIP5 and HCC-2. CCL15 is expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung.[1] It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3.[2][3] The human CCL15 gene spans four exons and is located in a head-to-tail orientation on chromosome 17 with the gene of another CC chemokine known as CCL14.[4]
|
| |||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| By family |
| ||||||||||||||||||||||||||||||||||||||||||
| By function/ cell |
| ||||||||||||||||||||||||||||||||||||||||||
 | This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it. |
