CREB-regulated transcription coactivator 1 (CRTC1), previously referred to as TORC1 (Transducer OfRegulated CREB activity 1), is a protein that in humans is encoded by the CRTC1 gene.[5][6][7][8] It is expressed in a limited number of tissues that include fetal brain and liver and adult heart, skeletal muscles, liver and salivary glands[9] and various regions of the adult central nervous system.[10]
Production of CRTC1 is blocked in Alzheimer's disease.[11]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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Coactivators |
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Corepressors |
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ATP-dependent remodeling factors |
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