REST corepressor 1 also known as CoREST is a protein that in humans is encoded by the RCOR1 gene.[5][6]
This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor).[6]
RCOR1 has been shown to interact with
PDB gallery
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2iw5: STRUCTURAL BASIS FOR COREST-DEPENDENT DEMETHYLATION OF NUCLEOSOMES BY THE HUMAN LSD1 HISTONE DEMETHYLASE
2uxn: STRUCTURAL BASIS OF HISTONE DEMETHYLATION BY LSD1 REVEALED BY SUICIDE INACTIVATION
2v1d: STRUCTURAL BASIS OF LSD1-COREST SELECTIVITY IN HISTONE H3 RECOGNITION
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Coactivators |
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Corepressors |
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ATP-dependent remodeling factors |
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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