Its generic name is "diphtheria and tetanus toxoids and acellular pertussis adsorbed, inactivated poliovirus and haemophilus B conjugate vaccine", and it is also known as DTaP-IPV-Hib.[1]
A branded formulation marketed in the United States is Pentacel, manufactured by Sanofi Pasteur.[3]
Pentacel is known in the UK and Canada as Pediacel.[4][5]
An equivalent vaccine marketed in the UK and Canada by GlaxoSmithKline is Infanrix IPV + Hib.[5] This is a two-part vaccine. The DTaP-IPV component is supplied as a sterile liquid, which is used to reconstitute lyophilized (freeze-dried) Hib vaccine.[citation needed]
It is only licensed for young children.[7] The United States Food and Drug Administration has approved[when?] the vaccine for children from age 6 weeks up to age 5 years.[1] It was used in the UK until 2017, following which a 6-in-1 vaccine became available containing the additional protection against Hepatitis B.[2]
^Plotkin SA, Liese J, Madhi SA, Ortiz E (July 2011). "A DTaP-IPV//PRP~T vaccine (Pentaxim): a review of 16 years' clinical experience". Expert Rev Vaccines. 10 (7): 981–1005. doi:10.1586/erv.11.72. PMID21749196. S2CID207224675.
Viruses
