Donald F. Steiner was born in 1930 in Lima, Ohio. He completed his B.S. in Chemistry and Zoology from the University of Cincinnati in 1952. He completed his M.S. in biochemistry and his M.D. from the University of Chicago in 1956.[3] He then completed his medical and research training – with an internship at King County Hospital and residency/post-doctoral research at the University of Washington – before returning to the University of Chicago as a faculty member in 1960.[3]
Steiner was promoted to full professor in 1968, and became chair of the department of biochemistry in 1973.[3] From 1985 to 2006, Steiner was a senior investigator of the Howard Hughes Medical Institute.[3]
In 1972, Steiner was elected to the American Academy of Arts and Sciences. The following year, he was elected to the National Academy of Sciences.[3]
Donald F. Steiner is known for his work in diabetes research, protein processing, and hormone biology.[3] In 1967, he published his discovery of proinsulin, precursor to the active hormone insulin.[3][4] He and his colleagues discovered some of the enzymes that convert proinsulin into insulin, and also devised methods for measuring insulin and its precursors in human serum.
In 1976 he received the Banting Medal for Scientific Achievement from the American Diabetes Association
In 1984/5, he was awarded the Wolf Prize in Medicine for "his discoveries concerning the bio-synthesis and processing of insulin which have had profound implications for basic biology and clinical medicine".[5][6]