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Contents

   



(Top)
  


1 See also  




2 References  




3 Further reading  













Fursultiamine






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From Wikipedia, the free encyclopedia
  

Fursultiamine
Skeletal formula of fursultiamine
Ball-and-stick model of the fursultiamine molecule
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral
ATC code
  • None
Legal status
Legal status
Identifiers

  • N-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-N-{(1E)-4-hydroxy-1-methyl-2-[(tetrahydrofuran-2-ylmethyl)disulfanyl]but-1-en-1-yl}formamide

CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.011.234 Edit this at Wikidata
Chemical and physical data
FormulaC17H26N4O3S2
Molar mass398.54 g·mol−1
3D model (JSmol)

  • O=CN(\C(=C(\SSCC1OCCC1)CCO)C)Cc2cnc(nc2N)C

Fursultiamine (INN; chemical name thiamine tetrahydrofurfuryl disulfideorTTFD; brand names Adventan, Alinamin-F, Benlipoid, Bevitol Lipophil, Judolor, Lipothiamine) is a medication and vitamin used to treat thiamine deficiency. Chemically, it is a disulfide derivative of thiamine and is similar in structure to allithiamine.[1]

It was synthesized in Japan in the 1960s from allithiamine for the purpose of developing forms of thiamine with improved lipophilicity for treating vitamin B1 deficiency (i.e., beriberi),[1] It was subsequently commercialized not only in Japan but also in Spain, Austria, Germany, and the United States.[2]

See also[edit]

References[edit]

  1. ^ a b Lonsdale D (September 2004). "Thiamine tetrahydrofurfuryl disulfide: a little known therapeutic agent". Medical Science Monitor. 10 (9): RA199–203. PMID 15328496.
  • ^ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. p. 1932. ISBN 3-88763-075-0.

    • Further reading[edit]


    Retrieved from "https://en.wikipedia.org/w/index.php?title=Fursultiamine&oldid=1148560216"
    Categories: 
    ●Drugs not assigned an ATC code
     ●Formamides
     ●Organic disulfides
     ●Aminopyrimidines
     ●Tetrahydrofurans
     ●Prodrugs
     ●Thiamine
     Hidden categories: 
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     ●Short description matches Wikidata
     ●Drugs with non-standard legal status
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     ●ECHA InfoCard ID from Wikidata
     ●Articles without KEGG source
     ●Articles without InChI source
     ●Articles containing unverified chemical infoboxes
      


    ●This page was last edited on 6 April 2023, at 22:39 (UTC).
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