Contents

Hypotaurine

Hypotaurine

Names
Preferred IUPAC name 2-Aminoethane-1-sulfinic acid
Identifiers
CAS Number	300-84-5 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:57853 Y
ChemSpider	96959 Y
ECHA InfoCard	100.155.825
KEGG	C00519 Y
PubChem CID	107812
UNII	5L08GE4332 Y
CompTox Dashboard (EPA)	DTXSID60861856 DTXSID8075380, DTXSID60861856
InChI InChI=1S/C2H7NO2S/c3-1-2-6(4)5/h1-3H2,(H,4,5) Y Key: VVIUBCNYACGLLV-UHFFFAOYSA-N Y InChI=1/C2H7NO2S/c3-1-2-6(4)5/h1-3H2,(H,4,5) Key: VVIUBCNYACGLLV-UHFFFAOYAM
SMILES O=S(O)CCN
Properties
Chemical formula	C2H7NO2S
Molar mass	109.15 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

Chemical compound

Hypotaurine is a sulfinic acid that is an intermediate in the biosynthesis of taurine. Like taurine, it also acts as an endogenous neurotransmitter via action on the glycine receptors.^[1] It is an osmolyte with antioxidant properties.^[2]

Hypotaurine is derived from cysteine (and homocysteine). In mammals, the biosynthesis of hypotaurine from cysteine occurs in the pancreas. In the cysteine sulfinic acid pathway, cysteine is first oxidized to its sulfinic acid, catalyzed by the enzyme cysteine dioxygenase. Cysteine sulfinic acid, in turn, is decarboxylated by sulfinoalanine decarboxylase to form hypotaurine. Hypotaurine is enzymatically oxidized to yield taurine by hypotaurine dehydrogenase.^[3]

References[edit]

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