Krueppel-like factor 5 is a protein that in humans is encoded by the KLF5 gene.[5][6]
This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.[6]
KLF5 has been shown to interact with Protein SET.[7]
KLF5 expression has been linked to higher survival rates for lung cancer patients.[8]
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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