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1 Chemistry  





2 Medical uses  





3 Other applications  





4 References  





5 External links  














Lanthanum carbonate






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From Wikipedia, the free encyclopedia
 


Lanthanum carbonate
Names
IUPAC name

Lanthanum carbonate

Other names

Fosrenol

Identifiers

CAS Number

3D model (JSmol)

ChEMBL
ChemSpider
ECHA InfoCard 100.008.728 Edit this at Wikidata
EC Number
  • 209-599-5
KEGG

PubChem CID

UNII

CompTox Dashboard (EPA)

  • InChI=1S/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6 checkY

    Key: NZPIUJUFIFZSPW-UHFFFAOYSA-H checkY

  • InChI=1/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6

    Key: NZPIUJUFIFZSPW-CYFPFDDLAT

  • [La+3].[La+3].O=C([O-])[O-].[O-]C([O-])=O.[O-]C([O-])=O

Properties

Chemical formula

La2(CO3)3
Molar mass 457.838 g/mol
Appearance White powder, hygroscopic
Density 2.6–2.7 g/cm3
Melting point decomposes

Solubility in water

negligible
Solubility soluble in acids
Pharmacology

ATC code

V03AE03 (WHO)
Legal status
Related compounds

Other anions

Lanthanum(III) oxide

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

☒N verify (what is checkY☒N ?)

Infobox references

Lanthanum carbonate, La2(CO3)3, is the salt formed by lanthanum(III) cations and carbonate anions. It is an ore of lanthanum metal (bastnäsite), along with monazite.

Chemistry[edit]

Lanthanum carbonate is used as a starting material in lanthanum chemistry, particularly in forming mixed oxides, for example

Medical uses[edit]

Lanthanum carbonate is used in medicine as a phosphate binder.[1] As a medication it is sold under the trade name Fosrenol by the pharmaceutical company Shire Pharmaceuticals. Due to its large size (1000 mg tablet is 2.2 cm in diameter), it may be possible to choke on the tablet if it is not chewed. It is prescribed for the treatment of hyperphosphatemia, primarily in patients with chronic kidney disease. It is taken with meals and binds to dietary phosphate, preventing phosphate from being absorbed by the intestine. For cats with hyperphosphatemia it is available under the trade name RenalzinbyBayer Animal Health.[2]

However, when lanthanum carbonate is used for treating hyperphosphatemia, its side effects, namely myalgia, muscular cramping, and peripheral edema, should be clinically monitored.[3]

Other applications[edit]

Lanthanum carbonate is also used for the tinting of glass,[citation needed] for water treatment, and as a catalyst for hydrocarbon cracking.

References[edit]

  1. ^ Editorial Staff (December 2004). "Lanthanum Carbonate". All Micromedex Systems. Micromedex, Inc. Archived from the original on 2007-09-14. Retrieved 2007-11-25.
  • ^ Bayer Animal Health (26 September 2008). "Bayer Animal Health launches Renalzin for Cats" (PDF). Archived from the original (PDF) on 7 July 2011. Retrieved 2008-09-30.
  • ^ Tonelli, Marcello; Pannu, Neesh; Manns, Braden (2010). "Oral Phosphate Binders in Patients with Kidney Failure". New England Journal of Medicine. 362 (14): 1312–24. doi:10.1056/NEJMra0912522. PMID 20375408. S2CID 22322676.
  • External links[edit]


    Retrieved from "https://en.wikipedia.org/w/index.php?title=Lanthanum_carbonate&oldid=1219663308"

    Categories: 
    Nephrology procedures
    Phosphate binders
    Lanthanum compounds
    Carbonates
    Metal-containing drugs
    Drugs developed by Takeda Pharmaceutical Company
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    ECHA InfoCard ID from Wikidata
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    This page was last edited on 19 April 2024, at 03:05 (UTC).

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