Neuronal Calcium Sensor is a large family of proteins which work as calcium dependent molecular switches and includes members like Frequenin (NCS1), recoverin, GCAP, neurocalcin, visinin etc.[1] All the members carry 4 EF hand motifs (out of which only 2 or 3 bind calcium) and an N-myristoyl group.[2]
KCNIP1, KCNIP2, Calsenilin or DREAM/KChIP-3/KCNIP3 (downstream regulatory element antagonist modulator/potassium channel interacting protein), KCNIP4
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Cell membrane |
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Intracellular signaling |
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Extracellular chelators |
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Calcium-binding domains |
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