TNFRSF19 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | TNFRSF19, TAJ, TAJ-alpha, TRADE, TROY, tumor necrosis factor receptor superfamily member 19, TNF receptor superfamily member 19 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 606122; MGI: 1352474; HomoloGene: 8481; GeneCards: TNFRSF19; OMA:TNFRSF19 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Tumor necrosis factor receptor superfamily, member 19, also known as TNFRSF19 and TROY is a human gene.[5]
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TNF receptor associated factor (TRAF) family members, and to activate c-Jun N-terminal kinases (JNK) signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.[5]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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Chemokine receptor (GPCRs) |
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TNF receptor |
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JAK-STAT |
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Ig superfamily |
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IL 17 family |
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Enzyme-linked receptor |
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