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F r o m W i k i p e d i a , t h e f r e e e n c y c l o p e d i a
Vonoprazan/amoxicillin/clarithromycin , sold under the brand name Vonosap among others, is a co-packaged medication used for the treatment of Helicobacter pylori (H. pylori ) infection.[1] [4] It contains vonoprazan (as the fumarate), a potassium-competitive acid blocker ; amoxicillin , a beta-lactam antibiotic ; and clarithromycin , a macrolide antibiotic .[1] [4]
It was approved for medical use in Japan in 2016,[3] and in the United States in May 2022.[1] [2] [5] [6] The US Food and Drug Administration (FDA) considers it to be a first-in-class medication .[7] [8]
References
[ edit ]
^ a b "Vonosap pack 400, Vonosap pack 800 and Vonopion pack (triple-drug blister packs containing Takecab tablet) Now Available for Helicobacter pylori[*] Eradication in Japan" . Takeda . 7 June 2016. Archived from the original on 10 May 2022. Retrieved 9 May 2022 .
^ a b Deguchi H, Yamazaki H, Kamitani T, Yamamoto Y, Fukuhara S (July 2021). "Impact of Vonoprazan Triple-Drug Blister Packs on H. pylori Eradication Rates in Japan: Interrupted Time Series Analysis" . Advances in Therapy . 38 (7 ): 3937–3947. doi :10.1007/s12325-021-01784-w . PMC 8280045 . PMID 34091865 .
^ "FDA NDA approval" (PDF) . U.S. Food and Drug Administration (FDA) . Archived (PDF) from the original on 12 May 2022. Retrieved 12 May 2022 .
^ "Voquezna Triple Pak (amoxicillin, clarithromycin, and vonoprazan) FDA Approval History" . Drugs.com .
^ "Advancing Health Through Innovation: New Drug Therapy Approvals 2022" . U.S. Food and Drug Administration (FDA) . 10 January 2023. Retrieved 22 January 2023 . This article incorporates text from this source, which is in the public domain .
^ New Drug Therapy Approvals 2022 (PDF) . U.S. Food and Drug Administration (FDA) (Report). January 2024. Archived from the original on 14 January 2024. Retrieved 14 January 2024 . This article incorporates text from this source, which is in the public domain .
Further reading
[ edit ]
Kajihara Y, Shimoyama T, Mizuki I (February 2017). "Analysis of the cost-effectiveness of using vonoprazan-amoxicillin-clarithromycin triple therapy for first-line Helicobacter pylori eradication". Scandinavian Journal of Gastroenterology . 52 (2 ): 238–241. doi :10.1080/00365521.2016.1250157 . PMID 27806639 . S2CID 25801431 .
Nishida T, Tsujii Y, Okamoto A, Tomita R, Higaki Y, Osugi N, et al. (9 July 2019). "A Triple-Drug Blister-Packaged Drug with Vonoprazan Improves First-Line Eradication of Helicobacter pylori in Elderly Patients: A Retrospective Propensity Score-Matched Cohort Study". Digestion . 101 (5 ): 608–614. doi :10.1159/000501608 . PMID 31288235 . S2CID 195871882 .
Okubo H, Akiyama J, Kobayakawa M, Kawazoe M, Mishima S, Takasaki Y, et al. (November 2020). "Vonoprazan-based triple therapy is effective for Helicobacter pylori eradication irrespective of clarithromycin susceptibility". Journal of Gastroenterology . 55 (11 ): 1054–1061. doi :10.1007/s00535-020-01723-6 . PMID 32930864 . S2CID 221674785 .
External links
[ edit ]
"Vonoprazan" . Drug Information Portal . U.S. National Library of Medicine.
"Amoxicillin" . Drug Information Portal . U.S. National Library of Medicine.
"Clarithromycin" . Drug Information Portal . U.S. National Library of Medicine.
t
e
R e t r i e v e d f r o m " https://en.wikipedia.org/w/index.php?title=Vonoprazan/amoxicillin/clarithromycin&oldid=1195535939 "
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