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Contents

   



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1 Synthesis  





2 References  














Irsogladine






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From Wikipedia, the free encyclopedia
 


Irsogladine
Names
Preferred IUPAC name

6-(2,5-Dichlorophenyl)1,3,5-triazine-2,4-diamine

Other names

DCPDAT, Dicloguamine, MN-1695.

Identifiers

CAS Number

ChemSpider

PubChem CID

UNII

CompTox Dashboard (EPA)

Properties

Chemical formula

C9H7Cl2N5
Molar mass 256.09 g·mol−1
Pharmacology

ATC code

A02BX16 (WHO)

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Infobox references

Irsogladine is a phosphodiesterase inhibitor.[1]

Antiulcer drug.

Synthesis

[edit]
ChemDrug Synthesis:[2][3] Patent:[4]

2,4-Dichloro-6-(2,5-dichlorophenyl)-1,3,5-triazine [61479-79-6] (1) (2) Dicyandiamide [461-58-5] (3) 2,5-Dichlorobenzonitrile [21663-61-6] (4)

References

[edit]
  1. ^ Satoh, H; Amagase, K; Takeuchi, K (2013). "Mucosal protective agents prevent exacerbation of NSAID-induced small intestinal lesions caused by antisecretory drugs in rats". The Journal of Pharmacology and Experimental Therapeutics. 348 (2): 227–35. doi:10.1124/jpet.113.208991. PMID 24254524. S2CID 23740642.
  • ^ Serradell, MN; Blancafort, P.; Castaer, J.; MN-1695. Drugs Fut 1983, 8, 6, 502.
  • ^ Ueda F, Aratani S, Mimura K, Kimura K, Nomura A, Enomoto H. Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals. Arzneimittelforschung. 1984;34(4):474-7. PMID: 654016.
  • ^ DE2506814 idem Hiromu Murai, 6 More », U.S. patent 3,966,728 (1976 to Nippon Shinyaku Co., Ltd.).

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  • Retrieved from "https://en.wikipedia.org/w/index.php?title=Irsogladine&oldid=1228083329"

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