| aminocarboxymuconate-semialdehyde decarboxylase | |||||||||
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aminocarboxymuconate-semialdehyde decarboxylase dimer, Human
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| Identifiers | |||||||||
| EC no. | 4.1.1.45 | ||||||||
| CAS no. | 37289-47-7 | ||||||||
| Alt. names | ACMSD | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) catalyzes the chemical reaction
2-aminomuconate semialdehyde + CO2This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. This enzyme participates in tryptophan metabolism. It has been identified as a marker in nonverbal autism.[1]
The systematic name of this enzyme class is 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming). Other names in common use include picolinic acid carboxylase, picolinic acid decarboxylase, alpha-amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase, alpha-amino-beta-carboxymuconate-epsilon-semialdehyde, beta-decarboxylase, 2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase, and 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase.
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Essential amino acids are in Capitals | |||||||||||||||||||||||||||||||||||||||||||
| K→acetyl-CoA |
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| 4.2.1: Hydro-Lyases |
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| 4.2.2: Acting on polysaccharides |
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| 4.2.3: Acting on phosphates |
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| 4.2.99: Other |
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This EC 4.1 enzyme-related article is a stub. You can help Wikipedia by expanding it. |
