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1 See also  




2 References  













RU-28306






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From Wikipedia, the free encyclopedia
  

RU-28306
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC13H16N2
Molar mass200.285 g·mol−1
3D model (JSmol)

  • c13c(C2)cccc1[nH]cc3CC2N(C)C

  • InChI=1S/C13H16N2/c1-15(2)11-6-9-4-3-5-12-13(9)10(7-11)8-14-12/h3-5,8,11,14H,6-7H2,1-2H3

  • Key:BQOANWOQEHVATQ-UHFFFAOYSA-N

RU-28306 is a synthetic indole alkaloid derivative which acts as a serotonin receptor agonist, with selectivity for 5-HT1 and 5-HT2 subtypes. It can be regarded either as a tricyclic derivative of DMT, or a structurally simplified analogue of LSD, but the binding affinityofracemic RU-28306 is closer to that of DMT, though with relatively higher affinity for 5-HT2 subtypes and lower for 5-HT1.[1] It has been sold as a designer drug and was first reported to the EMCDDA by a forensic laboratory in Slovenia in 2017.[2]

See also[edit]

References[edit]

  1. ^ Taylor EW, Nikam S, Weck B, Martin A, Nelson D (October 1987). "Relative selectivity of some conformationally constrained tryptamine analogs at 5-HT1, 5-HT1A and 5-HT2 recognition sites". Life Sciences. 41 (16): 1961–9. doi:10.1016/0024-3205(87)90749-1. PMID 3657392.
  • ^ EMCDDA – Europol 2017 Annual Report on the implementation of Council Decision 2005/387/JHA

    • Retrieved from "https://en.wikipedia.org/w/index.php?title=RU-28306&oldid=1176071492"
    Categories: 
    ●Serotonin receptor agonists
     ●Tryptamines
     ●Phenethylamines
     ●Heterocyclic compounds with 3 rings
     ●Indoles
     ●Dimethylamino compounds
     Hidden categories: 
    ●Articles with short description
     ●Short description matches Wikidata
     ●Articles without EBI source
     ●Chemical pages without DrugBank identifier
     ●Articles without KEGG source
     ●Drugs missing an ATC code
     ●Drugs with no legal status
     ●Articles containing unverified chemical infoboxes
      


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