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A p p e a r a n c e
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( T o p )
1
R e f e r e n c e s
2
E x t e r n a l l i n k s
T o g g l e t h e t a b l e o f c o n t e n t s
R i b o n u c l e a s e Z
4 l a n g u a g e s
● 日 本 語
● С р п с к и / s r p s k i
● S r p s k o h r v a t s k i / с р п с к о х р в а т с к и
● 中 文
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● G e t s h o r t e n e d U R L
● D o w n l o a d Q R c o d e
● W i k i d a t a i t e m
P r i n t / e x p o r t
● D o w n l o a d a s P D F
● P r i n t a b l e v e r s i o n
A p p e a r a n c e
F r o m W i k i p e d i a , t h e f r e e e n c y c l o p e d i a
TRNase Z (EC 3.1.26.11 , 3 tRNase , tRNA 3 endonuclease , RNase Z , 3' tRNase ) is an enzyme [1] [2] [3] [4] [5] [6] [7] that, among other things, catalyses the reactions involved in the maturation of tRNAs . Here, it endonucleolytically cleaves the RNA and removes extra 3' nucleotides from the tRNA precursor, generating the 3' termini of tRNAs . A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule. Similarly, it processes tRNA-like molecules such as mascRNA .[8]
References
[ edit ]
^ Mayer M, Schiffer S, Marchfelder A (February 2000). "tRNA 3' processing in plants: nuclear and mitochondrial activities differ". Biochemistry . 39 (8 ): 2096–105. doi :10.1021/bi992253e . PMID 10684660 .
^ Schiffer S, Helm M, Théobald-Dietrich A, Giegé R, Marchfelder A (July 2001). "The plant tRNA 3' processing enzyme has a broad substrate spectrum". Biochemistry . 40 (28 ): 8264–72. doi :10.1021/bi0101953 . PMID 11444972 .
^ Kunzmann A, Brennicke A, Marchfelder A (January 1998). "5' end maturation and RNA editing have to precede tRNA 3' processing in plant mitochondria" . Proceedings of the National Academy of Sciences of the United States of America . 95 (1 ): 108–13. doi :10.1073/pnas.95.1.108 . PMC 18142 . PMID 9419337 .
^ Mörl M, Marchfelder A (January 2001). "The final cut. The importance of tRNA 3'-processing" . EMBO Reports . 2 (1 ): 17–20. doi :10.1093/embo-reports/kve006 . PMC 1083803 . PMID 11252717 .
^ Minagawa A, Takaku H, Takagi M, Nashimoto M (April 2004). "A novel endonucleolytic mechanism to generate the CCA 3' termini of tRNA molecules in Thermotoga maritima" . The Journal of Biological Chemistry . 279 (15 ): 15688–97. doi :10.1074/jbc.M313951200 . PMID 14749326 .
^ Takaku H, Minagawa A, Takagi M, Nashimoto M (May 2003). "A candidate prostate cancer susceptibility gene encodes tRNA 3' processing endoribonuclease" . Nucleic Acids Research . 31 (9 ): 2272–8. doi :10.1093/nar/gkg337 . PMC 154223 . PMID 12711671 .
^ Wilusz JE, Freier SM, Spector DL (November 2008). "3' end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA" . Cell . 135 (5 ): 919–32. doi :10.1016/j.cell.2008.10.012 . PMC 2722846 . PMID 19041754 .
External links
[ edit ]
t
e
Activity
Regulation
Classification
Kinetics
Types
R e t r i e v e d f r o m " https://en.wikipedia.org/w/index.php?title=Ribonuclease_Z&oldid=1231227560 "
C a t e g o r y :
● E C 3 . 1 . 2 6
H i d d e n c a t e g o r i e s :
● A r t i c l e s w i t h s h o r t d e s c r i p t i o n
● S h o r t d e s c r i p t i o n m a t c h e s W i k i d a t a
● T h i s p a g e w a s l a s t e d i t e d o n 2 7 J u n e 2 0 2 4 , a t 0 5 : 1 9 ( U T C ) .
● T e x t i s a v a i l a b l e u n d e r t h e C r e a t i v e C o m m o n s A t t r i b u t i o n - S h a r e A l i k e L i c e n s e 4 . 0 ;
a d d i t i o n a l t e r m s m a y a p p l y . B y u s i n g t h i s s i t e , y o u a g r e e t o t h e T e r m s o f U s e a n d P r i v a c y P o l i c y . W i k i p e d i a ® i s a r e g i s t e r e d t r a d e m a r k o f t h e W i k i m e d i a F o u n d a t i o n , I n c . , a n o n - p r o f i t o r g a n i z a t i o n .
● P r i v a c y p o l i c y
● A b o u t W i k i p e d i a
● D i s c l a i m e r s
● C o n t a c t W i k i p e d i a
● C o d e o f C o n d u c t
● D e v e l o p e r s
● S t a t i s t i c s
● C o o k i e s t a t e m e n t
● M o b i l e v i e w