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Contents

   



(Top)
  


1 See also  




2 References  













α-Difluoromethyl-DOPA






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From Wikipedia, the free encyclopedia
  
(Redirected from Alpha-Difluoromethyl-DOPA)
α-Difluoromethyl-DOPA
Skeletal formula
Ball-and-stick model of α-difluoromethyl-DOPA
Names
Systematic IUPAC name

(2S)-2-Amino-2-[(3,4-dihydroxyphenyl)methyl]-3,3-difluoropropanoic acid

Other names

α-(Difluoromethyl)-3-hydroxy-L-tyrosine

Identifiers

CAS Number

3D model (JSmol)
  • Interactive image
    • ChemSpider
    MeSH alpha-difluoromethyl-DOPA

    PubChem CID
    UNII

    CompTox Dashboard (EPA)

    • InChI=1S/C10H11F2NO4/c11-8(12)10(13,9(16)17)4-5-1-2-6(14)7(15)3-5/h1-3,8,14-15H,4,13H2,(H,16,17)/t10-/m1/s1 checkY

      Key: XZVHHLNLLVICFA-SNVBAGLBSA-N checkY

    • InChI=1/C10H11F2NO4/c11-8(12)10(13,9(16)17)4-5-1-2-6(14)7(15)3-5/h1-3,8,14-15H,4,13H2,(H,16,17)/t10-/m1/s1

      Key: XZVHHLNLLVICFA-SNVBAGLBBM

    • C1=CC(=C(C=C1C[C@@](C(F)F)(C(=O)O)N)O)O

    • FC(F)[C@](C(=O)O)(N)Cc1cc(O)c(O)cc1

    Properties

    Chemical formula

    		 C10H11F2NO4
    Molar mass 247.20 g/mol
    Density 1.528 g/mL
    Boiling point 479 °C (894 °F; 752 K)

    Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

    ☒N verify (what is checkY☒N ?)

    Infobox references

    α-Difluoromethyl-3,4-dihydroxyphenylalanine (DFMD, DFM-DOPA) is a DOPA decarboxylase inhibitor.[1]

    See also

    [edit]

    References

    [edit]
    1. ^ Zbinden G, Brändle E (February 1980). "Inhibition of 5-hydroxytryptophan nephrotoxicity by alpha-difluoromethyl-dopa, an inhibitor or L-amino acid decarboxylase". Toxicology Letters. 5 (2): 125–9. doi:10.1016/0378-4274(80)90161-7. PMID 6781106.



    Retrieved from "https://en.wikipedia.org/w/index.php?title=Α-Difluoromethyl-DOPA&oldid=1175820068"
    Categories: 
    ●Aromatic L-amino acid decarboxylase inhibitors
     ●Alpha-Amino acids
     ●Catecholamines
     ●Organofluorides
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