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Clinical data | |
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Routes of administration | Oral |
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ECHA InfoCard | 100.038.481 ![]() |
Chemical and physical data | |
Formula | C10H10N2O3 |
Molar mass | 206.201 g·mol−1 |
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Caroxazone (Surodil, Timostenil) is an antidepressant which was formerly used for the treatment of depression but is now no longer marketed.[2][3] It acts as a reversible monoamine oxidase inhibitor (RIMA) of both MAO-A and MAO-B subtypes, with five-fold preference for the latter.[4][5][6][7][8]
Synthesis starts by reductive aminationofsalicylaldehyde and glycinamide to give 3. The synthesis is completed by reaction with phosgene and NaHCO3.
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