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1 See also  





2 References  














Mebanazine






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Mebanazine
Clinical data
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 1-phenylethylhydrazine

CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.559 Edit this at Wikidata
Chemical and physical data
FormulaC8H12N2
Molar mass136.198 g·mol−1

Mebanazine (trade name Actomol) is a monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was previously used as an antidepressant in the 1960s, but has since been withdrawn due to hepatotoxicity.[1][2][3]

Mebanazine in animals is claimed to be a more potent MAOI than pheniprazine with a greater therapeutic index.[4]

See also[edit]

References[edit]

  1. ^ Gilmour SJ (September 1965). "Clinical trial of mebanazine--a new monoamine oxidase inhibitor". The British Journal of Psychiatry. 111 (478): 899–902. doi:10.1192/bjp.111.478.899. PMID 5889715. S2CID 46651861.
  • ^ Barker JC, Jan IA, Enoch MD (November 1965). "A controlled trial of mebanazine ('Actomol') in depression". The British Journal of Psychiatry. 111 (480): 1095–100. doi:10.1192/bjp.111.480.1095. PMID 5320546. S2CID 6803488.
  • ^ Knott F (1965). "A preliminary trial of mebanazine in depressive states". The Journal of New Drugs. 5 (6): 345–7. doi:10.1002/j.1552-4604.1965.tb00259.x. PMID 5327282.
  • ^ Biel, J. H. (1967). "Annual Reports in Medicinal Chemistry". Chapter 2. Antidepressants, Stimulants, Hallucinogens. Annual Reports in Medicinal Chemistry. Vol. 2. Elsevier. pp. 11–23. doi:10.1016/S0065-7743(08)61499-2. ISBN 9780120405022.

  • t
  • e

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=Mebanazine&oldid=1206222379"

    Categories: 
    Drugs not assigned an ATC code
    Hepatotoxins
    Hydrazines
    Monoamine oxidase inhibitors
    Withdrawn drugs
    Nervous system drug stubs
    Hidden categories: 
    Articles with short description
    Short description matches Wikidata
    Drugs with non-standard legal status
    ECHA InfoCard ID from Wikidata
    Chemical pages without DrugBank identifier
    Articles without KEGG source
    Articles without InChI source
    Articles containing unverified chemical infoboxes
    All stub articles
     



    This page was last edited on 11 February 2024, at 15:07 (UTC).

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