| Erythromycin 12 hydroxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.154 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Erythromycin 12 hydroxylase (EC 1.14.13.154, EryK) is an enzyme with systematic name erythromycin-D,NADPH:oxygen oxidoreductase (12-hydroxylating) .[1][2][3] This enzyme catalyses the following chemical reaction
erythromycin C + NADP+ + H2OErythromycin 12 hydroxylase is responsible for the C-12 hydroxylation of the macrolactone ring.
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| CYP1 |
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| CYP2 |
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| CYP3 (CYP3A) |
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| CYP4 |
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| CYP5-20 |
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| CYP21-49 |
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| CYP51-69 |
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| CYP71-99 |
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| CYP101-281 |
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| CYP301-499 |
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| CYP501-699 |
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| CYP701-999 |
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