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Contents

   



(Top)
 


1 References  





2 External links  














Vesnarinone






Српски / srpski
Srpskohrvatski / српскохрватски

 

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From Wikipedia, the free encyclopedia
 


Vesnarinone
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
By mouth
ATC code
  • None
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 6-[4-(3,4-Dimethoxybenzoyl)piperazin-1-yl]-3,4-dihydro-1H-quinolin-2-one

CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H25N3O4
Molar mass395.459 g·mol−1
3D model (JSmol)
  • COC1=C(C=C(C=C1)C(=O)N2CCN(CC2)C3=CC4=C(C=C3)NC(=O)CC4)OC

  • InChI=1S/C22H25N3O4/c1-28-19-7-3-16(14-20(19)29-2)22(27)25-11-9-24(10-12-25)17-5-6-18-15(13-17)4-8-21(26)23-18/h3,5-7,13-14H,4,8-12H2,1-2H3,(H,23,26) ☒N

  • Key:ZVNYJIZDIRKMBF-UHFFFAOYSA-N ☒N

 ☒NcheckY (what is this?)  (verify)

Vesnarinone (INN) is a cardiotonic agent.[1] A mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. Vesnarinone improves ventricular performance most in patients with the worst degree of heart failure.

References

[edit]
  1. ^ Cavusoglu E, Frishman WH, Klapholz M (June 1995). "Vesnarinone: a new inotropic agent for treating congestive heart failure". Journal of Cardiac Failure. 1 (3): 249–257. doi:10.1016/1071-9164(95)90030-6. PMID 9420657.
[edit]
  • t
  • e

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=Vesnarinone&oldid=1134910955"

    Categories: 
    Drugs not assigned an ATC code
    N-benzoylpiperazines
    Inotropic agents
    PDE3 inhibitors
    Catechol ethers
    Phenylpiperazines
    2-Quinolones
    Cardiovascular system drug stubs
    Hidden categories: 
    Articles with short description
    Short description matches Wikidata
    Drugs with non-standard legal status
    Articles with changed ChemSpider identifier
    Articles with changed EBI identifier
    Articles with changed InChI identifier
    Chemical pages without DrugBank identifier
    Articles without KEGG source
    Drugboxes which contain changes to verified fields
    Drugboxes which contain changes to watched fields
    Commons category link from Wikidata
    All stub articles
     



    This page was last edited on 21 January 2023, at 12:06 (UTC).

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