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(Top)
 


1 Interactions  





2 References  





3 Further reading  














PSKH1






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From Wikipedia, the free encyclopedia
 


PSKH1

Identifiers

Aliases

PSKH1, protein serine kinase H1

External IDs

OMIM: 177015; MGI: 3528383; HomoloGene: 48461; GeneCards: PSKH1; OMA:PSKH1 - orthologs

Gene location (Human)

Chromosome 16 (human)

Chr.

Chromosome 16 (human)[1]

Chromosome 16 (human)

Genomic location for PSKH1

Genomic location for PSKH1

Band

16q22.1

Start

67,893,254 bp[1]

End

67,929,676 bp[1]

Gene location (Mouse)

Chromosome 8 (mouse)

Chr.

Chromosome 8 (mouse)[2]

Chromosome 8 (mouse)

Genomic location for PSKH1

Genomic location for PSKH1

Band

8|8 D3

Start

106,627,073 bp[2]

End

106,658,410 bp[2]

Bgee

Mouse (ortholog)


  • mucosa of transverse colon

  • apex of heart

  • body of stomach

  • body of pancreas

  • right coronary artery

  • popliteal artery

  • tibial arteries

  • left ovary

  • left adrenal cortex

  • genital tubercle

  • zygote

  • internal carotid artery

  • tail of embryo

  • external carotid artery

  • secondary oocyte

  • foot

  • maxillary prominence

  • mandibular prominence
  • More reference expression data

    BioGPS

    More reference expression data

    Molecular function

  • nucleotide binding
  • protein kinase activity
  • kinase activity
  • protein binding
  • ATP binding
  • protein serine/threonine kinase activity
  • Cellular component

  • Golgi apparatus
  • nuclear speck
  • endoplasmic reticulum membrane
  • membrane
  • plasma membrane
  • microtubule organizing center
  • endoplasmic reticulum
  • cytoskeleton
  • nucleus
  • intracellular anatomical structure
  • nucleoplasm
  • cellular component
  • Biological process

  • protein phosphorylation
  • heart development
  • determination of left/right symmetry
  • peptidyl-serine phosphorylation
  • peptidyl-threonine phosphorylation
  • intracellular signal transduction
  • Sources:Amigo / QuickGO

    Species

    Human

    Mouse

    Entrez

    Ensembl

    UniProt

    RefSeq (mRNA)

    NM_006742

    NM_173432

    RefSeq (protein)

    NP_006733

    NP_775608

    Location (UCSC)

    Chr 16: 67.89 – 67.93 Mb

    Chr 8: 106.63 – 106.66 Mb

    PubMed search

    [3]

    [4]

    Wikidata

    Serine/threonine-protein kinase H1 is an enzyme that in humans is encoded by the PSKH1 gene.[5][6]

    Interactions[edit]

    PSKH1 has been shown to interact with CDC6.[7]

    References[edit]

  • ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ Larsen F, Solheim J, Kristensen T, Kolstø AB, Prydz H (February 1994). "A tight cluster of five unrelated human genes on chromosome 16q22.1". Hum Mol Genet. 2 (10): 1589–95. doi:10.1093/hmg/2.10.1589. PMID 8268911.
  • ^ "Entrez Gene: PSKH1 protein serine kinase H1".
  • ^ Petersen BO, Lukas J, Sørensen CS, Bartek J, Helin K (January 1999). "Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization". EMBO J. 18 (2): 396–410. doi:10.1093/emboj/18.2.396. PMC 1171134. PMID 9889196.
  • Further reading[edit]

  • Petersen BO, Lukas J, Sørensen CS, Bartek J, Helin K (1999). "Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization". EMBO J. 18 (2): 396–410. doi:10.1093/emboj/18.2.396. PMC 1171134. PMID 9889196.
  • Amarzguioui M, Brede G, Babaie E, Grotli M, Sproat B, Prydz H (2000). "Secondary structure prediction and in vitro accessibility of mRNA as tools in the selection of target sites for ribozymes". Nucleic Acids Res. 28 (21): 4113–24. doi:10.1093/nar/28.21.4113. PMC 113158. PMID 11058107.
  • Brede G, Solheim J, Tröen G, Prydz H (2001). "Characterization of PSKH1, a novel human protein serine kinase with centrosomal, golgi, and nuclear localization". Genomics. 70 (1): 82–92. doi:10.1006/geno.2000.6365. PMID 11087665.
  • Brede G, Solheim J, Prydz H (2002). "PSKH1, a novel splice factor compartment-associated serine kinase". Nucleic Acids Res. 30 (23): 5301–9. doi:10.1093/nar/gkf648. PMC 137962. PMID 12466556.
  • Brede G, Solheim J, Stang E, Prydz H (2004). "Mutants of the protein serine kinase PSKH1 disassemble the Golgi apparatus". Exp. Cell Res. 291 (2): 299–312. doi:10.1016/j.yexcr.2003.07.009. PMID 14644153.
  • Serine/threonine-specific protein kinases (EC 2.7.11.1-EC 2.7.11.20)

  • LATS2
  • MAST1
  • MAST2
  • STK38
  • STK38L
  • CIT
  • ROCK1
  • SGK
  • SGK2
  • SGK3
  • Protein kinase B
  • Ataxia telangiectasia mutated
  • mTOR
  • EIF-2 kinases
  • Wee1
  • Pyruvate dehydrogenase kinase (EC 2.7.11.2)

  • PDK2
  • PDK3
  • PDK4
  • Dephospho-(reductase kinase) kinase (EC 2.7.11.3)

  • PRKAA2
  • β
  • γ
  • 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase (EC 2.7.11.4)

  • BCKDHA
  • BCKDHB
  • (isocitrate dehydrogenase (NADP+)) kinase (EC 2.7.11.5)

  • IDH3A
  • IDH3B
  • IDH3G
  • (tyrosine 3-monooxygenase) kinase (EC 2.7.11.6)

    Myosin-heavy-chain kinase (EC 2.7.11.7)

  • Aurora B kinase
  • Aurora C kinase
  • Fas-activated serine/threonine kinase (EC 2.7.11.8)

  • STK10
  • Goodpasture-antigen-binding protein kinase (EC 2.7.11.9)

    • -

    IκB kinase (EC 2.7.11.10)

  • IKK2
  • TBK1
  • IKBKE
  • IKBKG
  • IKBKAP
  • cAMP-dependent protein kinase (EC 2.7.11.11)

  • PRKACG
  • PRKACB
  • PRKACA
  • PRKY
  • cGMP-dependent protein kinase (EC 2.7.11.12)

  • PRKG1
  • Protein kinase C (EC 2.7.11.13)

  • Protein kinase Cζ
  • PKC alpha
  • PRKCB1
  • PRKCD
  • PRKCE
  • PRKCH
  • PRKCG
  • PRKCI
  • PRKCQ
  • Protein kinase N1
  • PKN2
  • PKN3
  • Rhodopsin kinase (EC 2.7.11.14)

    Beta adrenergic receptor kinase (EC 2.7.11.15)

  • Beta adrenergic receptor kinase-2
  • G-protein coupled receptor kinases (EC 2.7.11.16)

  • GRK5
  • GRK6
  • Ca2+/calmodulin-dependent (EC 2.7.11.17)

  • CAMK1
  • CAMK1A
  • CAMK1B
  • CAMK1D
  • CAMK1G
  • CAMK2
  • CAMK2A
  • CAMK2B
  • CAMK2D
  • CAMK2G
  • CAMK4
  • MLCK
  • CASK
  • CHEK1
  • CHEK2
  • DAPK1
  • DAPK2
  • DAPK3
  • STK11
  • MAPKAPK2
  • MAPKAPK3
  • MAPKAPK5
  • MARK1
  • MARK2
  • MARK3
  • MARK4
  • MELK
  • MKNK1
  • MKNK2
  • NUAK1
  • NUAK2
  • OBSCN
  • PASK
  • PHKG1
  • PHKG2
  • PIM1
  • PIM2
  • PKD1
  • PRKD2
  • PRKD3
  • PSKH1
  • SNF1LK2
  • KIAA0999
  • STK40
  • SNF1LK
  • SNRK
  • SPEG
  • TSSK2
  • Kalirin
  • TRIB1
  • TRIB2
  • TRIB3
  • TRIO
  • Titin
  • DCLK1
  • Myosin light-chain kinase (EC 2.7.11.18)

  • MYLK2
  • MYLK3
  • MYLK4
  • Phosphorylase kinase (EC 2.7.11.19)

  • PHKA2
  • PHKB
  • PHKG1
  • PHKG2
  • Elongation factor 2 kinase (EC 2.7.11.20)

  • STK19
  • Polo kinase (EC 2.7.11.21)

  • PLK2
  • PLK3
  • PLK4
  • Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30)

    Polo kinase (EC 2.7.11.21)

  • PLK2
  • PLK3
  • PLK4
  • Cyclin-dependent kinase (EC 2.7.11.22)

  • CDK2
  • CDKL2
  • CDK3
  • CDK4
  • CDK5
  • CDKL5
  • CDK6
  • CDK7
  • CDK8
  • CDK9
  • CDK10
  • CDK12
  • CDC2L5
  • PCTK1
  • PCTK2
  • PCTK3
  • PFTK1
  • CDC2L1
  • (RNA-polymerase)-subunit kinase (EC 2.7.11.23)

  • RPS6KA4
  • P70S6 kinase
  • P70-S6 Kinase 1
  • RPS6KB2
  • RPS6KA2
  • RPS6KA3
  • RPS6KA1
  • RPS6KC1
  • Mitogen-activated protein kinase (EC 2.7.11.24)

  • MAPK3
  • MAPK4
  • MAPK6
  • MAPK7
  • MAPK12
  • MAPK15
  • C-Jun N-terminal
  • P38 mitogen-activated protein
  • MAP3K (EC 2.7.11.25)

  • MAP3K2
  • MAP3K3
  • MAP3K4
  • MAP3K5
  • MAP3K6
  • MAP3K7
  • MAP3K8
  • RAFs
  • MLKs
  • CDC7
  • MAP3K14
  • Tau-protein kinase (EC 2.7.11.26)

  • TTK
  • GSK-3
  • (acetyl-CoA carboxylase) kinase (EC 2.7.11.27)

    • -

    Tropomyosin kinase (EC 2.7.11.28)

    • -

    Low-density-lipoprotein receptor kinase (EC 2.7.11.29)

    • -

    Receptor protein serine/threonine kinase (EC 2.7.11.30)

  • BMPR1A
  • BMPR1B
  • BMPR2
  • ACVR1
  • ACVR1B
  • ACVR1C
  • ACVR2A
  • ACVR2B
  • ACVRL1
  • Anti-Müllerian hormone receptor
  • MAP2K2
  • MAP2K3
  • MAP2K4
  • MAP2K5
  • MAP2K6
  • MAP2K7
  • Activity

  • Binding site
  • Catalytic triad
  • Oxyanion hole
  • Enzyme promiscuity
  • Diffusion-limited enzyme
  • Cofactor
  • Enzyme catalysis
  • Regulation

  • Cooperativity
  • Enzyme inhibitor
  • Enzyme activator
  • Classification

  • Enzyme superfamily
  • Enzyme family
  • List of enzymes
  • Kinetics

  • Eadie–Hofstee diagram
  • Hanes–Woolf plot
  • Lineweaver–Burk plot
  • Michaelis–Menten kinetics
  • Types

  • EC2 Transferases (list)
  • EC3 Hydrolases (list)
  • EC4 Lyases (list)
  • EC5 Isomerases (list)
  • EC6 Ligases (list)
  • EC7 Translocases (list)

  • t
  • e

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=PSKH1&oldid=1201419709"

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    This page was last edited on 31 January 2024, at 15:54 (UTC).

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