Rac2 (Ras-related C3 botulinum toxin substrate 2) is a small (~21 kDa) signaling G protein (to be specific, a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases.[5] It is encoded by the gene RAC2.[6]
Members of Rho family of GTPases appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases.[6]
Rac2 has been shown to interact with ARHGDIA[7][8] and Nitric oxide synthase 2A.[9]
PDB gallery
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1ds6: CRYSTAL STRUCTURE OF A RAC-RHOGDI COMPLEX
1e96: STRUCTURE OF THE RAC/P67PHOX COMPLEX
1foe: CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THE GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1
1g4u: CRYSTAL STRUCTURE OF THE SALMONELLA TYROSINE PHOSPHATASE AND GTPASE ACTIVATING PROTEIN SPTP BOUND TO RAC1
1he1: CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE GAP DOMAIN OF THE PSEUDOMONAS AERUGINOSA EXOS TOXIN AND HUMAN RAC
1hh4: RAC1-RHOGDI COMPLEX INVOLVED IN NADPH OXIDASE ACTIVATION
1i4d: CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP COMPLEXED WITH ARFAPTIN (P21)
1i4l: CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP IN COMPLEX WITH ARFAPTIN (P41)
1i4t: CRYSTAL STRUCTURE ANALYSIS OF RAC1-GMPPNP IN COMPLEX WITH ARFAPTIN
1mh1: SMALL G-PROTEIN
2fju: Activated Rac1 bound to its effector phospholipase C beta 2
2g0n: The Crystal Structure of the Human RAC3 in complex with GDP and Chloride
2h7v: Co-crystal structure of YpkA-Rac1
2ic5: Crystal structure of human RAC3 grown in the presence of Gpp(NH)p.
2nz8: N-terminal DHPH cassette of Trio in complex with nucleotide-free Rac1
2ov2: The crystal structure of the human RAC3 in complex with the CRIB domain of human p21-activated kinase 4 (PAK4)
2p2l: Rac1-GDP-Zinc Complex
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3.6.1 |
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3.6.2 |
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3.6.3-4: ATPase |
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3.6.5: GTPase |
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