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1 Uses  




2 References  













Suprofen






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From Wikipedia, the free encyclopedia
  

Suprofen
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
Routes of
administration		Oral, eye drops
ATC code
Legal status
Legal status
  • Discontinued
Pharmacokinetic data
Protein binding20%
Identifiers

  • (RS)-2-[4-(2-thienylcarbonyl)phenyl]propanoic acid

CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.050.071 Edit this at Wikidata
Chemical and physical data
FormulaC14H12O3S
Molar mass260.31 g·mol−1
3D model (JSmol)

  • O=C(c1ccc(cc1)C(C(=O)O)C)c2sccc2

  • InChI=1S/C14H12O3S/c1-9(14(16)17)10-4-6-11(7-5-10)13(15)12-3-2-8-18-12/h2-9H,1H3,(H,16,17) ☒N

  • Key:MDKGKXOCJGEUJW-UHFFFAOYSA-N ☒N

 ☒NcheckY (what is this?)  (verify)

Suprofen is a nonsteroidal anti-inflammatory drug (NSAID) developed by Janssen Pharmaceutica[1] that was marketed as 1% eye drops under the trade name Profenal.

Uses[edit]

Suprofen was originally used as tablet, but oral uses have been discontinued due to renal effects.[2] It was subsequently used exclusively as a topical ophthalmic solution, typically to prevent miosis during and after ophthalmic surgery.[3] This application has been discontinued as well, at least in the US.[4]

References[edit]

  1. ^ DE 2353357, Janssen PA, Van Daele GH, Boey JM, "Antiphlogistic aroyl-substituted phenylacetic acid derivatives", issued 1974 
  • ^ Nies AS (1988). "Renal Effects of Nonsteroidal Anti-Inflammatory Drugs". Basis for Variability of Response to Anti-Rheumatic Drugs. Vol. 24. pp. 95–106. doi:10.1007/978-3-0348-9160-8_9 (inactive 2024-02-09). ISBN 978-3-0348-9931-4. PMID 3142236. {{cite book}}: |journal= ignored (help)CS1 maint: DOI inactive as of February 2024 (link)
  • ^ "Pharmacy Compounding". Guidance for FDA Staff and Industry Compliance Policy Guides Manual. U.S. Food and Drug Administration. Archived from the original on 1 January 2009.
  • ^ "Suprofen ophthalmic". Drugs.com. Archived from the original on 2021-09-09. Retrieved 2018-01-23.
    • Stub icon

    This drug article relating to the musculoskeletal system is a stub. You can help Wikipedia by expanding it.

  • t
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    • Retrieved from "https://en.wikipedia.org/w/index.php?title=Suprofen&oldid=1212929246"
    Categories: 
    ●Nonsteroidal anti-inflammatory drugs
     ●Thiophenes
     ●Propionic acids
     ●Aromatic ketones
     ●Janssen Pharmaceutica
     ●Musculoskeletal system drug stubs
     Hidden categories: 
    ●CS1 errors: periodical ignored
     ●CS1 maint: DOI inactive as of February 2024
     ●Articles with short description
     ●Short description is different from Wikidata
     ●Drugs with non-standard legal status
     ●Articles with changed ChemSpider identifier
     ●Articles with changed EBI identifier
     ●ECHA InfoCard ID from Wikidata
     ●Articles with changed InChI identifier
     ●Drugboxes which contain changes to verified fields
     ●Drugboxes which contain changes to watched fields
     ●All stub articles
      


    ●This page was last edited on 10 March 2024, at 07:05 (UTC).
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