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1 References  













Trimazosin






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From Wikipedia, the free encyclopedia
  

Trimazosin
Clinical data
ATC code
Identifiers

  • (2-Hydroxy-2-methylpropyl) 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate

CAS Number
  • HCl: 53746-46-6 checkY
    • PubChem CID
    ChemSpider
    UNII
  • HCl: 827T79ILE7 checkY
    • KEGG
    ChEMBL
    CompTox Dashboard (EPA)
    ECHA InfoCard100.047.924 Edit this at Wikidata
    Chemical and physical data
    FormulaC20H29N5O6
    Molar mass435.481 g·mol−1
    3D model (JSmol)

    • O=C(OCC(O)(C)C)N3CCN(c1nc(N)c2c(n1)c(OC)c(OC)c(OC)c2)CC3

    • InChI=1S/C20H29N5O6/c1-20(2,27)11-31-19(26)25-8-6-24(7-9-25)18-22-14-12(17(21)23-18)10-13(28-3)15(29-4)16(14)30-5/h10,27H,6-9,11H2,1-5H3,(H2,21,22,23) ☒N

    • Key:YNZXWQJZEDLQEG-UHFFFAOYSA-N ☒N

     ☒NcheckY (what is this?)  (verify)

    Trimazosin is a sympatholytic alpha-1 blocker.[1][2]

    References[edit]

    1. ^ van Kalken CK, van der Meulen J, Oe PL, Vriesendorp R, Donker AJ (1986). "Pharmacokinetics of trimazosin and its effects on blood pressure, renal function and proteinuria during short-term therapy of patients with impaired renal function and hypertension". Eur. J. Clin. Pharmacol. 31 (1): 63–8. doi:10.1007/BF00870988. PMID 3780829. S2CID 19123951.
  • ^ U.S. patent 3,669,968



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  • t
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    • Retrieved from "https://en.wikipedia.org/w/index.php?title=Trimazosin&oldid=1107916922"
    Categories: 
    ●Alpha-1 blockers
     ●Carbamates
     ●Phenol ethers
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