Names | |
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Preferred IUPAC name
4-(2-{[7-Amino-2-(furan-2-yl)[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol | |
Identifiers | |
3D model (JSmol) |
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ChEMBL | |
ChemSpider |
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ECHA InfoCard | 100.216.533 |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C16H15N7O2 | |
Molar mass | 337.343 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
ZM-241,385 is a high affinity antagonist ligand selective for the adenosine A2A receptor.[1]
In animal models, ZM-241,385 has been shown to protect against beta amyloid neurotoxicity and therefore may be useful as a treatment for Alzheimer's disease.[2] ZM-241,385 has also been shown to enhance L-DOPA derived dopamine release and therefore may be useful in the treatment of Parkinson's disease.[3]
ZM+241385 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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