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Contents

   



(Top)
 


1 Types  





2 See also  





3 References  














Amino acid neurotransmitter






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From Wikipedia, the free encyclopedia
 


Activity at an axon terminal: Neuron A is transmitting a signal at the axon terminal to neuron B (receiving). Features: 1. Mitochondrion. 2. synaptic vesicle with neurotransmitters. 3. Autoreceptor. 4. Synapse with neurotransmitter released (serotonin). 5. Postsynaptic receptors activated by neurotransmitter (induction of a postsynaptic potential). 6. Calcium channel. 7. Exocytosis of a vesicle. 8. Recaptured neurotransmitter.

Anamino acid neurotransmitter is an amino acid which is able to transmit a nerve message across a synapse. Neurotransmitters (chemicals) are packaged into vesicles that cluster beneath the axon terminal membrane on the presynaptic side of a synapse in a process called endocytosis.[1]

Amino acid neurotransmitter release (exocytosis) is dependent upon calcium Ca2+ and is a presynaptic response.

Types[edit]

Excitatory amino acids (EAA) will activate post-synaptic cells.[2] inhibitory amino acids (IAA) depress the activity of post-synaptic cells.[2]

Amino acid[3][4] Excitatory or inhibitory
Aspartic acid Excitatory
β-alanine Inhibitory
Cysteine Excitatory
GABA (adult human brain) Inhibitory (adult); excitatory (developing)
Glycine Inhibitory
Glutamic acid Excitatory
Homocysteine Excitatory
Taurine Inhibitory

See also[edit]

References[edit]

  1. ^ "Axon Terminal : on Medical Dictionary Online". Archived from the original on 14 January 2009. Retrieved 2008-12-25.
  • ^ a b D'haenen, Hugo; den Boer, Johan A. (2002). Biological Psychiatry (digitised online by Google books). Paul Willner. John Wiley and Sons. p. 415. ISBN 978-0-471-49198-9. Retrieved 2008-12-26.
  • ^ Dalangin, R; Kim, A; Campbell, RE (27 August 2020). "The Role of Amino Acids in Neurotransmission and Fluorescent Tools for Their Detection". International Journal of Molecular Sciences. 21 (17): 6197. doi:10.3390/ijms21176197. PMC 7503967. PMID 32867295.
  • ^ Foye, William O.; Lemke, Thomas L. (2007). Foye's Principles of Medicinal Chemistry. David A. Williams. Lippincott Williams & Wilkins. p. 446. ISBN 978-0-7817-6879-5.

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=Amino_acid_neurotransmitter&oldid=1175509490"

    Categories: 
    Neurochemistry
    Molecular neuroscience
    Amino acids
    Acidic amino acids
    Neurotransmitters
    Amino acid neurotransmitters
    Hidden categories: 
    Articles with short description
    Short description matches Wikidata
     



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