Contents

CLNS1A

Protein-coding gene in humans

CLNS1A
Identifiers
Aliases	CLNS1A, CLCI, CLNS1B, ICln, chloride nucleotide-sensitive channel 1A
External IDs	OMIM: 602158; MGI: 109638; HomoloGene: 990; GeneCards: CLNS1A; OMA:CLNS1A - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q14.1 Start 77,514,936 bp[1] End 77,637,794 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 E1|7 53.57 cM Start 97,345,841 bp[2] End 97,370,003 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone Achilles tendon ganglionic eminence body of pancreas right adrenal gland right adrenal cortex left ovary C1 segment left adrenal gland monocyte Top expressed in motor neuron primitive streak medial ganglionic eminence condyle fossa vestibular membrane of cochlear duct hair follicle Rostral migratory stream renal corpuscle internal carotid artery More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein heterodimerization activity protein binding RNA binding Cellular component plasma membrane cytoskeleton nucleoplasm nucleus methylosome pICln-Sm protein complex cytosol cytoplasm Biological process cell volume homeostasis chloride transport spliceosomal snRNP assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1207 12729 Ensembl ENSG00000074201 ENSMUSG00000025439 UniProt P54105 Q61189 Q923F1 RefSeq (mRNA) NM_001311202 NM_001293 NM_001311199 NM_001311200 NM_001311201 NM_023671 RefSeq (protein) NP_001284 NP_001298128 NP_001298129 NP_001298130 NP_001298131 NP_076160 Location (UCSC) Chr 11: 77.51 – 77.64 Mb Chr 7: 97.35 – 97.37 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Methylosome subunit pICln is a protein that in humans is encoded by the CLNS1A gene.^[5][6][7]

CLNS1A has been shown to interact with:

• ITGA2B,^[8]
• PRMT5,^{[9][10][11][12]}
• SNRPD1,^[9] and
• SNRPD3.^[9]

• Chloride channel

• CLNS1A+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• Human CLNS1A genome location and CLNS1A gene details page in the UCSC Genome Browser.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.