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Contents

   



(Top)
 


1 Function  





2 See also  





3 References  





4 Further reading  





5 External links  














KCNK7






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From Wikipedia, the free encyclopedia
 


KCNK7
Identifiers
AliasesKCNK7, K2p7.1, TWIK3, potassium two pore domain channel subfamily K member 7
External IDsOMIM: 603940; MGI: 1341841; HomoloGene: 43131; GeneCards: KCNK7; OMA:KCNK7 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_033456
NM_005714
NM_033347
NM_033348
NM_033455

NM_001004138
NM_010609

RefSeq (protein)

NP_005705
NP_203133
NP_203134
NP_258416

NP_034739

Location (UCSC)Chr 11: 65.59 – 65.6 MbChr 19: 5.75 – 5.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Potassium channel, subfamily K, member 7, also known as KCNK7orK2P7.1 is a protein which is encoded in humans by the KCNK7 gene. K2P7.1 is a potassium channel containing two pore-forming P domains.[5][6][7] Multiple transcript variants encoding different isoforms have been found for this gene.[8]

Function[edit]

This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel; It may require other non-pore-forming proteins for activity.[8]

See also[edit]

References[edit]

  • ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ Salinas M, Reyes R, Lesage F, Fosset M, Heurteaux C, Romey G, Lazdunski M (April 1999). "Cloning of a new mouse two-P domain channel subunit and a human homologue with a unique pore structure". J. Biol. Chem. 274 (17): 11751–60. doi:10.1074/jbc.274.17.11751. PMID 10206991.
  • ^ Goldstein SA, Bockenhauer D, O'Kelly I, Zilberberg N (March 2001). "Potassium leak channels and the KCNK family of two-P-domain subunits". Nat. Rev. Neurosci. 2 (3): 175–84. doi:10.1038/35058574. PMID 11256078. S2CID 9682396.
  • ^ Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (December 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol. Rev. 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106. S2CID 7356601.
  • ^ a b "Entrez Gene: potassium channel".
  • Further reading[edit]

  • Goldstein SA, Bockenhauer D, O'Kelly I, Zilberberg N (2001). "Potassium leak channels and the KCNK family of two-P-domain subunits". Nat. Rev. Neurosci. 2 (3): 175–84. doi:10.1038/35058574. PMID 11256078. S2CID 9682396.
  • Salinas M, Reyes R, Lesage F, et al. (1999). "Cloning of a new mouse two-P domain channel subunit and a human homologue with a unique pore structure". J. Biol. Chem. 274 (17): 11751–60. doi:10.1074/jbc.274.17.11751. PMID 10206991.
  • Medhurst AD, Rennie G, Chapman CG, et al. (2001). "Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and periphery". Brain Res. Mol. Brain Res. 86 (1–2): 101–14. doi:10.1016/S0169-328X(00)00263-1. PMID 11165377.
  • External links[edit]


  • t
  • e

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=KCNK7&oldid=1142717360"

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    This page was last edited on 4 March 2023, at 00:30 (UTC).

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