Contents

HCN3

Protein-coding gene in the species Homo sapiens

HCN3
Identifiers
Aliases	HCN3, hyperpolarization activated cyclic nucleotide gated potassium channel 3
External IDs	OMIM: 609973; MGI: 1298211; HomoloGene: 22453; GeneCards: HCN3; OMA:HCN3 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q22 Start 155,277,463 bp[1] End 155,289,848 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F1 Start 89,053,381 bp[2] End 89,067,503 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum testicle ganglionic eminence mucosa of transverse colon ventricular zone pituitary gland anterior pituitary hypothalamus superior frontal gyrus right frontal lobe Top expressed in neural layer of retina perirhinal cortex entorhinal cortex pineal gland barrel cortex CA3 field spinal ganglia glossopharyngeal ganglion olfactory bulb choroid plexus of fourth ventricle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding potassium channel activity cAMP binding sodium channel activity voltage-gated ion channel activity ion channel activity voltage-gated potassium channel activity voltage-gated sodium channel activity protein binding Cellular component integral component of membrane membrane plasma membrane synapse neuronal cell body axon dendrite cone cell pedicle integral component of plasma membrane Biological process sodium ion transmembrane transport sodium ion transport cellular response to dopamine regulation of membrane potential regulation of ion transmembrane transport ion transport potassium ion transport response to cisplatin transmembrane transport potassium ion transmembrane transport cellular response to cAMP Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57657 15168 Ensembl ENSG00000143630 ENSG00000263324 ENSMUSG00000028051 UniProt Q9P1Z3 O88705 RefSeq (mRNA) NM_020897 NM_008227 RefSeq (protein) NP_065948 NP_032253 Location (UCSC) Chr 1: 155.28 – 155.29 Mb Chr 3: 89.05 – 89.07 Mb PubMed search [3] [4]
Wikidata
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Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 is a protein that in humans is encoded by the HCN3 gene.^[5][6]

See also[edit]

• Cyclic nucleotide-gated ion channel

References[edit]

Further reading[edit]

External links[edit]

• HCN3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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