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TRPC2

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TRPC2

Identifiers

Aliases

TRPC2, transient receptor potential cation channel subfamily C member 2, pseudogene, transient receptor potential cation channel subfamily C member 2 (pseudogene)

External IDs

GeneCards: TRPC2; OMA:TRPC2 - orthologs

Gene location (Human)

Chr.	Chromosome 11 (human)^[1]

Band	11p15.4	Start	3,616,679 bp^[1]
Band	11p15.4	End	3,637,672 bp^[1]

Orthologs

Species

Human

Mouse

Entrez


7221


n/a

Ensembl


ENSG00000182048


n/a

UniProt


n a


n/a

RefSeq (mRNA)


n/a


n/a

RefSeq (protein)


n/a


n/a

Location (UCSC)

Chr 11: 3.62 – 3.64 Mb

n/a

PubMed search

^[2]

n/a

Wikidata

View/Edit Human

Transient receptor potential cation channel, subfamily C, member 2, also known as TRPC2, is a protein that in humans is encoded by the TRPC2 pseudogene. This protein is not expressed in humans but is in certain other species such as mouse.^[3]

Interactions

[edit]

TRPC2 has been shown to interact with TRPC6.^[4]

References

[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000182048 – Ensembl, May 2017

^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

^ Clapham DE, Julius D, Montell C, Schultz G (December 2005). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100. S2CID 17936350.

^ Chu, Xin; Tong Qin; Cheung Joseph Y; Wozney Jocelyn; Conrad Kathleen; Mazack Virginia; Zhang Wenyi; Stahl Richard; Barber Dwayne L; Miller Barbara A (Mar 2004). "Interaction of TRPC2 and TRPC6 in erythropoietin modulation of calcium influx". J. Biol. Chem. 279 (11). United States: 10514–22. doi:10.1074/jbc.M308478200. ISSN 0021-9258. PMID 14699131.

External links

[edit]

TRPC2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Membrane transport protein: ion channels (TC 1A)

Ca²⁺: Calcium channel

Ligand-gated

Inositol trisphosphate receptor
- 1
- 2
- 3
Ryanodine receptor
- 1
- 2
- 3

Voltage-gated

L-type/Ca_vα
- 1.1
- 1.2
- 1.3
- 1.4
N-type/Ca_vα2.2
P-type/Ca_vα
- 2.1
Q-type/Ca_vα2.1
R-type/Ca_vα2.3
T-type/Ca_vα
- 3.1
- 3.2
- 3.3

α₂δ-subunits
- 1
- 2
β-subunits
- β1
- β2
- β3
- β4
γ-subunits
- γ1
- γ2
- γ3
- γ4

Cation channels of sperm
- 1
- 2
- 3
- 4
Two-pore channel
- 1
- 2

Na⁺: Sodium channel

Constitutively active

Epithelial sodium channel
- α
- β
- γ
- δ

Proton-gated

Amiloride-sensitive cation channel
- 1
- 2
- 3
- 4

Voltage-gated

Na_vα
- 1.1
- 1.2
- 1.3
- 1.4
- 1.5
- 1.6
- 1.7
- 1.8
- 1.9
- 7A
Na_vβ
- 1
- 2
- 3
- 4

K⁺: Potassium channel

Calcium-activated	BK channel α1 β1 β2 β3 β4 SK channel SK1 SK2 SK3 IK channel IK1 K_Ca 1.1 2.1 2.2 2.3 3.1 4.1 4.2 5.1
Inward-rectifier	K_ATP K_ir 1.1 2.1 2.2 2.3 2.4 2.6 GIRK/K_ir 3.1 3.2 3.3 3.4 K_ir 4.1 4.2 5.1 6.1 6.2 7.1
Tandem pore domain	K2P 1 2 3 4 5 6 7 9 10 12 13 15 16 17 18
Voltage-gated	K_vα1-6 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 2.1 2.2 3.1 3.2 3.3 3.4 4.1 4.2 4.3 5.1 6.1 6.2 6.3 6.4 K_vα7-12 7.1 7.2 7.3 7.4 7.5 8.1 8.2 9.1 9.2 9.3 10.1 10.2 11.1/hERG 11.2 11.3 12.1 12.2 12.3 K_vβ 1 2 3 KCNIP 1 2 3 4 minK/ISK minK/ISK-like MiRP 1 2 3 Shaker (gene)

Miscellaneous

Cl⁻: Chloride channel	Calcium-activated chloride channels Anoctamin ANO1 Bestrophin 1 2 Chloride Channel Accessory 1 2 3 4 CFTR CLCN 1 2 3 4 5 6 7 KA KB CLIC 1 2 3 4 5 6 L1 CLNS 1A 1B
H⁺: Proton channel	HVCN1
M⁺: CNG cation channel	α 1 2 3 4 β 1 2 3 HCN FC 1 2 3 4
M⁺: TRP cation channel	TRPA (1) TRPC 1 2 3 4 4AP 5 6 7 TRPM 1 2 3 4 5 6 7 8 TRPML 1 2 3 TRPN TRPP 1 2 TRPV 1 2 3 4 5 6
H₂O (+ solutes): Porin	Aquaporin 0 1 2 3 4 5 6 7 8 9 Voltage-dependent anion channel 1 2 3 General bacterial porin family
Cytoplasm: Gap junction	Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin