Names | |
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IUPAC name
N-(aminomethylidene)-L-glutamic acid | |
Other names
FIGLU | |
Identifiers | |
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3D model (JSmol) |
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ChemSpider |
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ECHA InfoCard | 100.011.308 |
MeSH | Formiminoglutamic+acid |
PubChem CID |
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UNII | |
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Properties | |
C6H10N2O4 | |
Molar mass | 174.156 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Formiminoglutamic acid (FIGLU; conjugate base, formiminoglutamate) is an intermediate in the catabolismofL-histidinetoL-glutamic acid. It thus is also a biomarker for intracellular levels of folate. The FIGLU test is used to identify vitamin B₁₂ deficiency, folate deficiency, and liver failureorliver disease.[1][2] It is elevated with folate trapping, where it is accompanied by decreased methylmalonic acid, increased folate and a decrease in homocysteine.[3]
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K→acetyl-CoA |
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