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Mg2+-importing ATPase







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From Wikipedia, the free encyclopedia
 

(Redirected from ATP3)

magnesium-importing ATPase
Identifiers
EC no.3.6.3.2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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Inenzymology, a Mg2+-importing ATPase (EC 3.6.3.2) is an enzyme that catalyzes the chemical reaction

ATP + H2O + Mg2+out ADP + phosphate + Mg2+in

The 3 substrates of this enzyme are ATP, H2O, and Mg2+, whereas its 3 products are ADP, phosphate, and Mg2+.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (Mg2+-importing).

The mgtA gene which encodes this enzyme is thought to be regulated by a magnesium responsive RNA element.[1] A human enzyme was found in erythrocytes[2] but the observation could not be confirmed.

References[edit]

  1. ^ Groisman EA, Cromie MJ, Shi Y, Latifi T (2006). "A Mg2+-responding RNA that controls the expression of a Mg2+ transporter". Cold Spring Harb Symp Quant Biol. 71: 251–8. doi:10.1101/sqb.2006.71.005. PMID 17381304.
  • ^ Szemraj J, Sobolewska B, Gulczynska E, Wilczynski J, Zylinska L (May 2005). "Magnesium sulfate effect on erythrocyte membranes of asphyxiated newborns". Clin. Biochem. 38 (5): 457–64. doi:10.1016/j.clinbiochem.2005.02.005. PMID 15820777.
  • Kaczmarek MT, Maguire ME (1998). "The CorA Mg2+ transport protein of Salmonella typhimurium Mutagenesis of conserved residues in the third membrane domain identifies a Mg2+ pore". J. Biol. Chem. 273 (44): 28663–9. doi:10.1074/jbc.273.44.28663. PMID 9786860.

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  • Retrieved from "https://en.wikipedia.org/w/index.php?title=Mg2%2B-importing_ATPase&oldid=1172353601"

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    Enzymes of unknown structure
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    This page was last edited on 26 August 2023, at 14:58 (UTC).

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