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Clebopride






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From Wikipedia, the free encyclopedia
  

Clebopride
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers

  • 4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-
    2-methoxybenzamide

CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.054.424 Edit this at Wikidata
Chemical and physical data
FormulaC20H24ClN3O2
Molar mass373.88 g·mol−1
3D model (JSmol)

  • Clc1cc(c(OC)cc1N)C(=O)NC3CCN(Cc2ccccc2)CC3

  • InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25) checkY

  • Key:BVPWJMCABCPUQY-UHFFFAOYSA-N checkY

  (verify)

Clebopride is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. Chemically, it is a substituted benzamide, closely related to metoclopramide.

A small Spanish study found that more adverse reactions are reported with clebopride than with metoclopramide, particularly extrapyramidal symptoms.[1]

References[edit]

  1. ^ Cuena Boy R, Maciá Martínez MA (March 1998). "[Extrapyramidal toxicity caused by metoclopramide and clebopride: study of voluntary notifications of adverse effects to the Spanish Drug Surveillance System]". Atencion Primaria (in Spanish). 21 (5): 289–95. PMID 9608114. Free full text Archived 2018-11-01 at the Wayback Machine
Stub icon

This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it.

  • t
  • e

    • Retrieved from "https://en.wikipedia.org/w/index.php?title=Clebopride&oldid=1189620850"
    Categories: 
    ●Antiemetics
     ●Dopamine antagonists
     ●4-Amino-N-(3-(diethylamino)propyl)-2-methoxybenzamides
     ●Piperidines
     ●Chloroarenes
     ●Gastrointestinal system drug stubs
     Hidden categories: 
    ●CS1 Spanish-language sources (es)
     ●Webarchive template wayback links
     ●Articles with short description
     ●Short description is different from Wikidata
     ●ECHA InfoCard ID from Wikidata
     ●Chemical pages without DrugBank identifier
     ●Drugs with no legal status
     ●Drugboxes which contain changes to watched fields
     ●All stub articles
      


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