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F r o m W i k i p e d i a , t h e f r e e e n c y c l o p e d i a
British biochemist (born 1943)
Sir Richard John Roberts FRS [4] biochemist and molecular biologist . He was awarded the 1993 Nobel Prize in Physiology or Medicine with Phillip Allen Sharp for the discovery of introns in eukaryotic DNA and the mechanism of gene-splicing . He currently works at New England Biolabs .[8] [9] [10]
Early life and education [ edit ]
Roberts was born in Derby , the son of Edna (Allsop) and John Roberts, an auto mechanic.[11] Bath . In Bath, he attended City of Bath Boys' School .[11] detective and then, when given a chemistry set , a chemist . In 1965 he graduated from the University of Sheffield with a Bachelor of Science degree in chemistry followed by a PhD in 1969.[3] phytochemical studies of neoflavonoids and isoflavonoids .[12] [13]
Career and research [ edit ]
During 1969–1972, he did postdoctoral research at Harvard University .[11] Cold Spring Harbor Laboratory ,[14] James Dewey Watson , a co-discoverer of the structure of DNA and a fellow Nobel laureate. In this period he also visited the MRC Laboratory of Molecular Biology for the first time, working alongside Fred Sanger .[15] [14] New England Biolabs .[11] Phillip Allen Sharp .[16]
Roberts's discovery of the alternative splicing of genes, in particular, has had a profound impact on the study and applications of molecular biology.[4] adenovirus ,[14] genetics , and has led to the discovery of split genes in higher organisms, including human beings.[4] [10]
Awards and honours [ edit ]
In 1992, Roberts received an honorary doctorate from the Faculty of Medicine at Uppsala University , Sweden .[17] University of Bath in 1994.[18] American Academy of Achievement in 1994.[19] Lomonosov Gold Medal of the Russian Academy of Sciences.[6]
Roberts was elected a Fellow of the Royal Society (FRS) in 1995 [4] member of the European Molecular Biology Organization (EMBO) in the same year.[5] University of Sheffield , where he had been a student, was named after him. A refurbished science department at Beechen Cliff School (previously City of Bath Boys' School) was also named after Roberts, who had donated a substantial sum of his Nobel prize winnings to the school.[20]
Roberts is an atheist and was one of the signers of the Humanist Manifesto .[21] [22] knighted in the 2008 Birthday Honours.[23]
Roberts is a member of the Advisory Board of Patient Innovation ,[24]
Roberts has been a keynote speaker at the Congress of Future Medical Leaders (2014, 2015, 2016, 2020).[25]
He also is the chairman of The Laureate Science Alliance, a non-profit supporting research worldwide.
In 2016, Roberts and other Nobelists composed and signed a "Laureates Letter Supporting Precision Agriculture (GMOs)" addressed to the leaders of Greenpeace, the United Nations and global governments and Sir Roberts has advocated for Genetically Modified Organisms (GMOs) in general and Golden Rice in particular to advance health in developing countries, noting the high safety record of GM foods.[26] [27]
References [ edit ]
^ Carr, Kimberly (1993). "Nobel goes to discoverers of 'split genes' . Nature . 365 (6447): 597. Bibcode :1993Natur.365..597C . doi :10.1038/365597a0 PMID 8413620 .
^ a b c d e "ROBERTS, Sir Richard (John)" Who's Who Oxford University Press ed.). A & C Black.(Subscription or UK public library membership required.)
^ a b c d e Anon (1995). "Sir Richard Roberts FRS" . London: Royal Society . Archived from the original on 6 October 2015.
"All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License .” --"Royal Society Terms, conditions and policies" . Archived from the original on 25 September 2015. Retrieved 9 March 2016 .{{cite web }}: CS1 maint: bot: original URL status unknown (link )
^ a b Anon (2016). "Richard J. Roberts EMBO profile" . people.embo.org . Heidelberg: European Molecular Biology Organization .
^ a b Lomonosov Gold Medal 2021 (in Russian)
^ Roberts, Richard John (2003). "A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes" . Nucleic Acids Research 31 7 ): 1805–1812. doi :10.1093/nar/gkg274 . PMC 152790 PMID 12654995 .
^ Roberts, R. J. ; Chang, Y. -C.; Hu, Z.; Rachlin, J. N.; Anton, B. P.; Pokrzywa, R. M.; Choi, H. -P.; Faller, L. L.; Guleria, J.; Housman, G.; Klitgord, N.; Mazumdar, V.; McGettrick, M. G.; Osmani, L.; Swaminathan, R.; Tao, K. R.; Letovsky, S.; Vitkup, D.; Segrè, D.; Salzberg, S. L.; Delisi, C.; Steffen, M.; Kasif, S. (2010). "COMBREX: A project to accelerate the functional annotation of prokaryotic genomes" . Nucleic Acids Research 39 doi :10.1093/nar/gkq1168 . PMC 3013729 PMID 21097892 .
^ Roberts, R. J. ; Varmus, H. E. ; Ashburner, M. ; Brown, P. O. ; Eisen, M. B. ; Khosla, C. ; Kirschner, M.; Nusse, R. ; Scott, M. (2001). "Information Access: Building A GenBank of the Published Literature". Science . 291 (5512): 2318–9. doi :10.1126/science.1060273 . PMID 11269300 . S2CID 34395787 .
^ a b Richard J. Roberts's publications indexed by the Scopus bibliographic database. (subscription required)
^ a b c d Anon (1993). "Richard J. Roberts - Biographical" . Nobel Foundation. Archived from the original on 4 March 2016. Retrieved 28 February 2016 .
^ Roberts, Richard John (1969). Phytochemical studies involving neoflavanoids and isoflavanoids copac.jisc.ac.uk (PhD thesis). University of Sheffield. OCLC 270832404 .
^ Richard J. Roberts ORCID 0000-0002-4348-0169
^ a b c Chow, Louise T.; Gelinas, Richard E.; Broker, Thomas R.; Roberts, Richard J. (1977). "An amazing sequence arrangement at the 5' ends of adenovirus 2 messenger RNA". Cell . 12 1 ): 1–8. doi :10.1016/0092-8674(77 )90180-5 . PMID 902310 . S2CID 2099968 .
^ "The Nobel Prize in Physiology or Medicine 1993" . NobelPrize.org . Retrieved 14 July 2023 .
^ Klimasauskas, Saulius; Kumar, Sanjay; Roberts, Richard J.; Cheng, Xiaodong (1994). "Hhal methyltransferase flips its target base out of the DNA helix". Cell . 76 2 ): 357–369. doi :10.1016/0092-8674(94 )90342-5 . PMID 8293469 . S2CID 23161543 .
^ "Honorary doctorates - Uppsala University, Sweden" . Uu.se . 17 August 2016. Retrieved 28 August 2016 .
^ "Honorary Graduates 1989 to present" . bath.ac.uk . University of Bath . Archived from the original on 19 December 2015. Retrieved 18 February 2012 .
^ "Golden Plate Awardees of the American Academy of Achievement" . achievement.org . American Academy of Achievement .
^ "Beechen Cliff School website" .[dead link
^ "Humanist Manifesto II" . American Humanist Association. Archived from the original on 20 October 2012. Retrieved 4 October 2012 .
^ Reville, William (2006). "A bright journey to atheism, or a road that ignores all the signs?" . The Irish Times the original on 5 March 2016.
^ https://www.independent.co.uk/news/uk/home-news/queens-birthday-honours-full-list-846831.html
^ Patient Innovation
^ "Speakers" . Congress of Future Medical Leaders . Retrieved 31 March 2020 .
^ Keith Edmisten (9 July 2018). " .
^ Ed Regis (8 October 2019). Golden Rice: The Imperiled Birth of a GMO Superfood . Johns Hopkins University Press. ISBN 978-1421433035
External links [ edit ]
Richard J. Roberts on Nobelprize.org An Amazing Distortion in DNA Induced by a Methyltransferase
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2001–present
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a d d i t i o n a l t e r m s m a y a p p l y . B y u s i n g t h i s s i t e , y o u a g r e e t o t h e T e r m s o f U s e a n d P r i v a c y P o l i c y . W i k i p e d i a ® i s a r e g i s t e r e d t r a d e m a r k o f t h e W i k i m e d i a F o u n d a t i o n , I n c . , a n o n - p r o f i t o r g a n i z a t i o n . ● P r i v a c y p o l i c y ● A b o u t W i k i p e d i a ● D i s c l a i m e r s ● C o n t a c t W i k i p e d i a ● C o d e o f C o n d u c t ● D e v e l o p e r s ● S t a t i s t i c s ● C o o k i e s t a t e m e n t ● M o b i l e v i e w ●
T o g g l e l i m i t e d c o n t e n t w i d t h
including the Nobel Lecture An Amazing Distortion in DNA Induced by a Methyltransferase
