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Find sources: "Brodimoprim" – news · newspapers · books · scholar · JSTOR (August 2014) |
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ECHA InfoCard | 100.054.745 |
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Formula | C13H15BrN4O2 |
Molar mass | 339.193 g·mol−1 |
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Melting point | 225 to 228 °C (437 to 442 °F) |
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Brodimoprim is a structural derivative of trimethoprim. In brodimoprim, the 4-methoxy group of trimethoprim is replaced with a bromine atom.
As trimethoprim, brodimoprim is a selective inhibitorofbacterial dihydrofolate reductase.[1]
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Antifolates (inhibit bacterial purine metabolism, thereby inhibiting DNA and RNA synthesis) |
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Quinolones (inhibit bacterial topoisomerase and/or DNA gyrase, thereby inhibiting DNA replication) |
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Anaerobic DNA inhibitors |
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RNA synthesis |
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